SCOPe 2.06: Domain d4d1pa_: 4d1p A:

Lineage for d4d1pa_ (4d1p A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187302] (35 PDB entries)

8. Domain d4d1pa_: 4d1p A: [260306]
   automated match to d3e7sa_
   complexed with act, btb, gd, gol, h4b, hem, q16, zn

Details for d4d1pa_

PDB Entry: 4d1p, 1.73 Å

PDB Description: structure of human endothelial nitric oxide synthase heme domain in complex with 6-((((3s, 5r)-5-(((6-amino-4-methylpyridin-2-yl)methoxy) methyl)pyrrolidin-3-yl)oxy) methyl)-4-methylpyridin-2-amine

PDB Compounds: (A:) Nitric oxide synthase, endothelial

SCOPe Domain Sequences for d4d1pa_:

Sequence, based on SEQRES records:

>d4d1pa_ d.174.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fprvknwevgsitydtlsaqaqqdgpctprrclgslvfprklqgrpspgppapeqllsqa
rdfinqyyssikrsgsqaheqrlqeveaevaatgtyqlreselvfgakqawrnaprcvgr
iqwgklqvfdardcrsaqemftyicnhikyatnrgnlrsaitvfpqrcpgrgdfriwnsq
lvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeppelfllpp
elvlevplehptlewfaalglrwyalpavsnmlleigglefpaapfsgwymsteigtrnl
cdphryniledvavcmdldtrttsslwkdkaaveinvavlhsyqlakvtivdhhaatasf
mkhleneqkarggcpadwawivppisgsltpvfhqemvnyflspafryqpdpw

Sequence, based on observed residues (ATOM records):

>d4d1pa_ d.174.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fprvknwevgsitydtlsaqaqqdgpctprrclgslvfpapeqllsqardfinqyyssik
rsgsqaheqrlqeveaevaatgtyqlreselvfgakqawrnaprcvgriqwgklqvfdar
dcrsaqemftyicnhikyatnrgnlrsaitvfpqrcpgrgdfriwnsqlvryagyrqqdg
svrgdpanveitelciqhgwtpgngrfdvlplllqapdeppelfllppelvlevplehpt
lewfaalglrwyalpavsnmlleigglefpaapfsgwymsteigtrnlcdphryniledv
avcmdldtrttsslwkdkaaveinvavlhsyqlakvtivdhhaatasfmkhleneqkarg
gcpadwawivppisgsltpvfhqemvnyflspafryqpdpw

Timeline for d4d1pa_:

• d4d1pa_ first appeared in SCOPe 2.04
  
• d4d1pa_ appears in SCOPe 2.05
  
• d4d1pa_ appears in SCOPe 2.07
  
• d4d1pa_ appears in the current release, SCOPe 2.08