SCOPe 2.08: Domain d4nz2b1: 4nz2 B:29-490

Lineage for d4nz2b1 (4nz2 B:29-490)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Mammalian cytochrome p450 2c9 [89118] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89119] (4 PDB entries)
   Uniprot P11712

8. Domain d4nz2b1: 4nz2 B:29-490 [258952]
   Other proteins in same PDB: d4nz2a2, d4nz2b2
   automated match to d1og5a_
   complexed with 2qj, gol, hem, so4

Details for d4nz2b1

PDB Entry: 4nz2, 2.45 Å

PDB Description: Crystal structure of CYP2C9 in complex with an inhibitor

PDB Compounds: (B:) Cytochrome P450 2C9

SCOPe Domain Sequences for d4nz2b1:

Sequence; same for both SEQRES and ATOM records:

>d4nz2b1 a.104.1.1 (B:29-490) Mammalian cytochrome p450 2c9 {Human (Homo sapiens) [TaxId: 9606]}
rppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvlhgyeavkeali
dlgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkrsiedrvqee
arclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlmeklnenieil
sspwiqvynnfpalldyfpgthnkllknvafmksyilekvkehqesmdmnnpqdfidcfl
mkmekekhnqpseftieslentavdlfgagtettsttlryalllllkhpevtakvqeeie
rvigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfrnylipkgttil
isltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgealagmelflf
ltsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipv

Timeline for d4nz2b1:

• d4nz2b1 first appeared in SCOPe 2.04, called d4nz2b_
  
• d4nz2b1 appears in SCOPe 2.07