SCOPe 2.06: Domain d3d2ra2: 3d2r A:181-397

Lineage for d3d2ra2 (3d2r A:181-397)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.0: automated matches [227160] (1 protein)
   not a true family

6. Protein automated matches [226867] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225008] (12 PDB entries)

8. Domain d3d2ra2: 3d2r A:181-397 [245605]
   Other proteins in same PDB: d3d2ra1, d3d2rb1
   automated match to d2bu8a2
   complexed with adp, gol, mg

Details for d3d2ra2

PDB Entry: 3d2r, 2.03 Å

PDB Description: Crystal structure of pyruvate dehydrogenase kinase isoform 4 in complex with ADP

PDB Compounds: (A:) [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4

SCOPe Domain Sequences for d3d2ra2:

Sequence, based on SEQRES records:

>d3d2ra2 d.122.1.0 (A:181-397) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sdsqtgnpshigsidpncdvvavvqdafecsrmlcdqyylsspelkltqvngkfpdqpih
ivyvpshlhhmlfelfknamratvehqenqpsltpievivvlgkedltikisdrgggvpl
riidrlfsytystaptpvmdnsrnaplagfgyglpisrlyakyfqgdlnlyslsgygtda
iiylkalssesieklpvfnksafkhyqmsseaddwci

Sequence, based on observed residues (ATOM records):

>d3d2ra2 d.122.1.0 (A:181-397) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sdshigsidpncdvvavvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvps
hlhhmlfelfknamratvehqenqpsltpievivvlgkedltikisdrgggvplriidrl
fsytystaptaplagfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesiek
lpvfnksafkhyddwci

Timeline for d3d2ra2:

• d3d2ra2 first appeared in SCOPe 2.04
  
• d3d2ra2 appears in SCOPe 2.05
  
• d3d2ra2 appears in SCOPe 2.07
  
• d3d2ra2 appears in the current release, SCOPe 2.08