SCOPe 2.06: Domain d4bo8c1: 4bo8 C:-5-247

Lineage for d4bo8c1 (4bo8 C:-5-247)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (239 species)
   not a true protein

7. Species Pseudomonas aeruginosa, PA01 [TaxId:208964] [196452] (27 PDB entries)

8. Domain d4bo8c1: 4bo8 C:-5-247 [234269]
   Other proteins in same PDB: d4bo8a2, d4bo8b2, d4bo8c2, d4bo8d2
   automated match to d4afna_
   complexed with 34x, so4

Details for d4bo8c1

PDB Entry: 4bo8, 2.7 Å

PDB Description: Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(2-amino-4- phenylimidazol-1-yl)-3-(2-fluorophenyl)urea at 2.7A resolution

PDB Compounds: (C:) 3-oxoacyl-[acyl-carrier-protein] reductase FabG

SCOPe Domain Sequences for d4bo8c1:

Sequence, based on SEQRES records:

>d4bo8c1 c.2.1.0 (C:-5-247) automated matches {Pseudomonas aeruginosa, PA01 [TaxId: 208964]}
nlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangv
egaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnllvrmkddewfdvvntnl
nslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaakaglegftralarevgs
raitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvt
gatvpvnggmyms

Sequence, based on observed residues (ATOM records):

>d4bo8c1 c.2.1.0 (C:-5-247) automated matches {Pseudomonas aeruginosa, PA01 [TaxId: 208964]}
nlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangv
egaglvldvssdesvaatlehiqqhlgqplivvnnagdewfdvvntnlnslyrlskavlr
gmtkarwgriinigsvvgagqtnyaaakaglegftralarevgsraitvnavapgfidtd
mtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

Timeline for d4bo8c1:

• d4bo8c1 first appeared in SCOPe 2.03, called d4bo8c_
  
• d4bo8c1 was called d4bo8c_ in SCOPe 2.05
  
• d4bo8c1 appears in SCOPe 2.07
  
• d4bo8c1 appears in the current release, SCOPe 2.08