SCOPe 2.06: Domain d4baea_: 4bae A:

Lineage for d4baea_ (4bae A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.0: automated matches [227160] (1 protein)
   not a true family

6. Protein automated matches [226867] (14 species)
   not a true protein

7. Species Mycobacterium smegmatis [TaxId:1772] [228578] (2 PDB entries)

8. Domain d4baea_: 4bae A: [234131]
   automated match to d4baed_
   complexed with ca, rwx, so4

Details for d4baea_

PDB Entry: 4bae, 2.35 Å

PDB Description: optimisation of pyrroleamides as mycobacterial gyrb atpase inhibitors: structure activity relationship and in vivo efficacy in the mouse model of tuberculosis

PDB Compounds: (A:) DNA gyrase subunit b

SCOPe Domain Sequences for d4baea_:

Sequence, based on SEQRES records:

>d4baea_ d.122.1.0 (A:) automated matches {Mycobacterium smegmatis [TaxId: 1772]}
gleavrkrpgmyigstgerglhhliwevvdnavdeamagfatrvdvkihadgsvevrddg
rgipvemhatgmptidvvmtqlhaggkfdgetyavsgglhgvgvsvvnalstrleatvlr
dgyewfqyydrsvpgklkqggetketgttirfwadpeifettdynfetvarrlqemafln
kgltieltderdgkhrvfhyp

Sequence, based on observed residues (ATOM records):

>d4baea_ d.122.1.0 (A:) automated matches {Mycobacterium smegmatis [TaxId: 1772]}
gleavrkrpgmyigstgerglhhliwevvdnavdeamagfatrvdvkihadgsvevrddg
rgipvemhatgmptidvvmtqlhgvgvsvvnalstrleatvlrdgyewfqyydrsvpgkl
kqggetketgttirfwadpeifettdynfetvarrlqemaflnkgltieltderdgkhrv
fhyp

Timeline for d4baea_:

• d4baea_ first appeared in SCOPe 2.03
  
• d4baea_ appears in SCOPe 2.05
  
• d4baea_ appears in SCOPe 2.07
  
• d4baea_ appears in the current release, SCOPe 2.08