SCOPe 2.05: Domain d2vuaa2: 2vua A:1080-1297

Lineage for d2vuaa2 (2vua A:1080-1297)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.4: STI-like [50386] (3 families)

5. Family b.42.4.2: Clostridium neurotoxins, C-terminal domain [50399] (3 proteins)
   overall fold is very similar to that of the STI family
   automatically mapped to Pfam PF07951

6. Protein automated matches [229100] (3 species)
   not a true protein

7. Species Clostridium botulinum [TaxId:1491] [229101] (3 PDB entries)

8. Domain d2vuaa2: 2vua A:1080-1297 [231349]
   Other proteins in same PDB: d2vuaa1
   automated match to d3btaa2

Details for d2vuaa2

PDB Entry: 2vua, 1.7 Å

PDB Description: crystal structure of the botulinum neurotoxin serotype a binding domain

PDB Compounds: (A:) botulinum neurotoxin a heavy chain

SCOPe Domain Sequences for d2vuaa2:

Sequence, based on SEQRES records:

>d2vuaa2 b.42.4.2 (A:1080-1297) automated matches {Clostridium botulinum [TaxId: 1491]}
nekeikdlydnqsnsgilkdfwgdylqydkpyymlnlydpnkyvdvnnvgirgymylkgp
rgsvmttniylnsslyrgtkfiikkyasgnkdnivrnndrvyinvvvknkeyrlatnasq
agvekilsaleipdvgnlsqvvvmkskndqgitnkckmnlqdnngndigfigfhqfnnia
klvasnwynrqierssrtlgcswefipvddgwgerplq

Sequence, based on observed residues (ATOM records):

>d2vuaa2 b.42.4.2 (A:1080-1297) automated matches {Clostridium botulinum [TaxId: 1491]}
nekeikdlydnqsnsgilkdfwgdylqydkpyymlnlydpnkyvdvnnvgirgymylkgp
rgsvmttniylnsslyrgtkfiikkyasgnkdnivrnndrvyinvvvknkeyrlatnasq
agvekilsaleipdvgnlsqvvvmksknditnkckmnlqdnngndigfigfhqfnniakl
vasnwynrqierssrtlgcswefipvddgwgerplq

Timeline for d2vuaa2:

• d2vuaa2 first appeared in SCOPe 2.03
  
• d2vuaa2 appears in SCOPe 2.04
  
• d2vuaa2 appears in SCOPe 2.06
  
• d2vuaa2 appears in the current release, SCOPe 2.08