SCOPe 2.07: Domain d3vqsa_: 3vqs A:

Lineage for d3vqsa_ (3vqs A:)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus [TaxId:11103] [187048] (44 PDB entries)

8. Domain d3vqsa_: 3vqs A: [194829]
   automated match to d3gnwb_
   protein/RNA complex; complexed with cl, jt1

Details for d3vqsa_

PDB Entry: 3vqs, 1.9 Å

PDB Description: crystal structure of hcv ns5b rna polymerase with a novel piperazine inhibitor

PDB Compounds: (A:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d3vqsa_:

Sequence; same for both SEQRES and ATOM records:

>d3vqsa_ e.8.1.4 (A:) automated matches {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpip
aasqldlsgwfva

Timeline for d3vqsa_:

• d3vqsa_ first appeared in SCOPe 2.02
  
• d3vqsa_ appears in SCOPe 2.06
  
• d3vqsa_ appears in the current release, SCOPe 2.08