SCOP 1.65: Domain d3hada1: 3had A:204-304

Lineage for d3hada1 (3had A:204-304)

1. Root: SCOP 1.65

2. Class a: All alpha proteins [46456] (179 folds)

3. Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
   multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry

4. Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (9 families)
   N-terminal domain is Rossmann-fold with a family-specific C-terminal extension

5. Family a.100.1.3: Short chain L-3-hydroxyacyl CoA dehydrogenase [48187] (1 protein)

6. Protein Short chain L-3-hydroxyacyl CoA dehydrogenase [48188] (2 species)
   Dimer of 5-helical motifs; similar to duplicated motifs of 6PGD and KARI

7. Species Human (Homo sapiens) [TaxId:9606] [48189] (7 PDB entries)

8. Domain d3hada1: 3had A:204-304 [18799]
   Other proteins in same PDB: d3hada2, d3hadb2

Details for d3hada1

PDB Entry: 3had, 2 Å

PDB Description: biochemical characterization and structure determination of human heart short chain l-3-hydroxyacyl coa dehydrogenase provide insight into catalytic mechanism

SCOP Domain Sequences for d3hada1:

Sequence; same for both SEQRES and ATOM records:

>d3hada1 a.100.1.3 (A:204-304) Short chain L-3-hydroxyacyl CoA dehydrogenase {Human (Homo sapiens)}
gfivnrllvpylmeairlyergdaskedidtamklgagypmgpfelldyvgldttkfivd
gwhemdaenplhqpspslnklvaenkfgkktgegfykykhh

Timeline for d3hada1:

• d3hada1 first appeared (with stable ids) in SCOP 1.55
  
• d3hada1 appears in SCOP 1.63
  
• d3hada1 appears in SCOP 1.67
  
• d3hada1 appears in the current release, SCOPe 2.08