SCOPe 2.02: Domain d3kqea_: 3kqe A:

Lineage for d3kqea_ (3kqe A:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein automated matches [190044] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (122 PDB entries)

8. Domain d3kqea_: 3kqe A: [179556]
   Other proteins in same PDB: d3kqel_
   automated match to d1c5md_
   complexed with lgm, na

Details for d3kqea_

PDB Entry: 3kqe, 2.35 Å

PDB Description: factor xa in complex with the inhibitor 3-methyl-1-(3-(5- oxo-4,5- dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'- (pyrrolidin-1-ylmethyl) biphenyl-4-yl)-5,6-dihydro-1h- pyrazolo[3,4-c]pyridin-7(4h)-one

PDB Compounds: (A:) factor Xa heavy chain

SCOPe Domain Sequences for d3kqea_:

Sequence; same for both SEQRES and ATOM records:

>d3kqea_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d3kqea_:

• d3kqea_ first appeared in SCOPe 2.01
  
• d3kqea_ appears in SCOPe 2.03
  
• d3kqea_ appears in the current release, SCOPe 2.08