SCOPe 2.08: Domain d3ixga_: 3ixg A:

Lineage for d3ixga_ (3ixg A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (19 proteins)
   in the multi-domain class (e), this applies to domains with different numbers of (sub)domains than the most common domain
   

6. Protein AMPC beta-Lactamase, class C [56618] (4 species)
   contains small alpha+beta subdomain inserted in the common fold

7. Species Escherichia coli, cephalosporinase [TaxId:562] [56621] (115 PDB entries)

8. Domain d3ixga_: 3ixg A: [178669]
   automated match to d1c3ba_
   complexed with bzb; mutant

Details for d3ixga_

PDB Entry: 3ixg, 2.14 Å

PDB Description: x-ray crystal structure of the extended-spectrum ampc t70i mutant beta-lactamase with and without benzo(b)thiophene-2-boronic acid bound at 2.14 angstrom resolution

PDB Compounds: (A:) Beta-lactamase

SCOPe Domain Sequences for d3ixga_:

Sequence, based on SEQRES records:

>d3ixga_ e.3.1.1 (A:) AMPC beta-Lactamase, class C {Escherichia coli, cephalosporinase [TaxId: 562]}
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktfigvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

Sequence, based on observed residues (ATOM records):

>d3ixga_ e.3.1.1 (A:) AMPC beta-Lactamase, class C {Escherichia coli, cephalosporinase [TaxId: 562]}
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktfigvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
ellrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplklnhtwi
nvpgvkstiedmarwvqsnlkpldinektlqqgiqlaqsrywqtgdmyqglgwemldwpv
npdsiiialaarpvkaitpptpavraswvhktgatggfgsyvafipekelgivmlankny
pnparvdaawqilnalq

Timeline for d3ixga_:

• d3ixga_ first appeared in SCOPe 2.01
  
• d3ixga_ appears in SCOPe 2.07