SCOPe 2.07: Domain d3i5kd1: 3i5k D:1-565

Lineage for d3i5kd1 (3i5k D:1-565)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus genotype 2a (isolate jfh-1) [TaxId:356411] [189047] (4 PDB entries)

8. Domain d3i5kd1: 3i5k D:1-565 [178102]
   Other proteins in same PDB: d3i5ka2, d3i5kb2, d3i5kc2, d3i5kd2
   automated match to d1nb4a_
   complexed with po4

Details for d3i5kd1

PDB Entry: 3i5k, 2.2 Å

PDB Description: Crystal structure of the NS5B polymerase from Hepatitis C Virus (HCV) strain JFH1

PDB Compounds: (D:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d3i5kd1:

Sequence; same for both SEQRES and ATOM records:

>d3i5kd1 e.8.1.4 (D:1-565) automated matches {Hepatitis C virus genotype 2a (isolate jfh-1) [TaxId: 356411]}
smsyswtgalitpcspeeeklpinplsnsllryhnkvycttsksasqrakkvtfdrtqvl
dahydsvlkdiklaaskvsarlltleeacqltpphsarskygfgakevrslsgravnhik
svwkdlledpqtpipttimaknevfcvdpakggkkparlivypdlgvrvcekmalyditq
klpqavmgasygfqyspaqrveyllkawaekkdpmgfsydtrcfdstvterdirteesiy
qacslpeeartaihslterlyvggpmfnskgqtcgyrrcrasgvlttsmgntitcyvkal
aackaagivaptmlvcgddlvvisesqgteedernlrafteamtrysappgdpprpeydl
elitscssnvsvalgprgrrryyltrdpttplaraawetvrhspinswlgniiqyaptiw
vrmvlmthffsilmvqdtldqnlnfemygsvysvnpldlpaiierlhgldafsmhtyshh
eltrvasalrklgapplrvwksraravraslisrggkaavcgrylfnwavktklkltplp
earlldlsswftvgagggdifhsvs

Timeline for d3i5kd1:

• d3i5kd1 first appeared in SCOPe 2.01, called d3i5kd_
  
• d3i5kd1 appears in SCOPe 2.06
  
• d3i5kd1 appears in the current release, SCOPe 2.08