SCOPe 2.06: Domain d3h11b_: 3h11 B:

Lineage for d3h11b_ (3h11 B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Caspase-8 [52135] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52136] (7 PDB entries)

8. Domain d3h11b_: 3h11 B: [177145]
   Other proteins in same PDB: d3h11a_
   automated match to d1i4eb_

Details for d3h11b_

PDB Entry: 3h11, 1.9 Å

PDB Description: zymogen caspase-8:c-flipl protease domain complex

PDB Compounds: (B:) caspase-8

SCOPe Domain Sequences for d3h11b_:

Sequence, based on SEQRES records:

>d3h11b_ c.17.1.1 (B:) Caspase-8 {Human (Homo sapiens) [TaxId: 9606]}
dkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfeik
phddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqftg
lkcpslagkpkvffiqacqgdnyqkgipvetaseeqpylemalsspqtryipdeadfllg
matvnncvsyrnpaegtwyiqslcqslrercprgddiltiltevnyevsnkddkknmgkq
mpqptftlrkklvfpsd

Sequence, based on observed residues (ATOM records):

>d3h11b_ c.17.1.1 (B:) Caspase-8 {Human (Homo sapiens) [TaxId: 9606]}
dkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfeik
phddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqftg
lkcpslagkpkvffiqacqgdnyqqtryipdeadfllgmatvnncvsyrnpaegtwyiqs
lcqslrercprgddiltiltevnyevsnkgkqmpqptftlrkklvfpsd

Timeline for d3h11b_:

• d3h11b_ first appeared in SCOPe 2.01
  
• d3h11b_ appears in SCOPe 2.05
  
• d3h11b_ appears in SCOPe 2.07
  
• d3h11b_ appears in the current release, SCOPe 2.08