SCOPe 2.07: Domain d3fqla1: 3fql A:2-565

Lineage for d3fqla1 (3fql A:2-565)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus genotype 1b (isolate con1) [TaxId:333284] [188792] (8 PDB entries)

8. Domain d3fqla1: 3fql A:2-565 [175981]
   Other proteins in same PDB: d3fqla2
   automated match to d1c2pb_
   complexed with 79z, gol

Details for d3fqla1

PDB Entry: 3fql, 1.8 Å

PDB Description: Hepatitis C virus polymerase NS5B (CON1 1-570) with HCV-796 inhibitor

PDB Compounds: (A:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d3fqla1:

Sequence, based on SEQRES records:

>d3fqla1 e.8.1.4 (A:2-565) automated matches {Hepatitis C virus genotype 1b (isolate con1) [TaxId: 333284]}
msytwtgalitpcaaeetklpinalsnsllrhhnlvyattsrsaslrqkkvtfdrlqvld
dhyrdvlkemkakastvkakllsveeackltpphsarskfgygakdvrnlsskavnhirs
vwkdlledtetpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvst
lpqavmgssygfqyspgqrveflvnawkakkcpmgfaydtrcfdstvtendirveesiyq
ccdlapearqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkaaa
acraaklqdctmlvcgddlvvicesagtqedeaslrafteamtrysappgdppkpeydle
litscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwa
rmilmthffsillaqeqlekaldcqiygacysiepldlpqiiqrlhglsafslhsyspge
inrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavrtklkltpipa
asqldlsswfvagysggdiyhsls

Sequence, based on observed residues (ATOM records):

>d3fqla1 e.8.1.4 (A:2-565) automated matches {Hepatitis C virus genotype 1b (isolate con1) [TaxId: 333284]}
msytwtgalitpcaaeetklpinalsnsllrhhnlvyattsrsaslrqkkvtfdrlqvld
dhyrdvlkemkakastvkakllsveeackltpphsarskfgygakdvrnlsskavnhirs
vwkdlledtetpidttimaknevfcvrkparlivfpdlgvrvcekmalydvvstlpqavm
gssygfqyspgqrveflvnawkakkcpmgfaydtrcfdstvtendirveesiyqccdlap
earqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkaaaacraak
lqdctmlvcgddlvvicesagtqedeaslrafteamtrysappgdppkpeydlelitscs
snvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmilmt
hffsillaqeqlekaldcqiygacysiepldlpqiiqrlhglsafslhsyspgeinrvas
clrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavrtklkltpipaasqldl
sswfvagysggdiyhsls

Timeline for d3fqla1:

• d3fqla1 first appeared in SCOPe 2.01, called d3fqla_
  
• d3fqla1 appears in SCOPe 2.06
  
• d3fqla1 appears in the current release, SCOPe 2.08