SCOPe 2.06: Domain d3f4xa_: 3f4x A:

Lineage for d3f4xa_ (3f4x A:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.74: Carbonic anhydrase [51068] (1 superfamily)
   single sheet; 10 strands

4. Superfamily b.74.1: Carbonic anhydrase [51069] (2 families)

5. Family b.74.1.1: Carbonic anhydrase [51070] (2 proteins)
   automatically mapped to Pfam PF00194

6. Protein Carbonic anhydrase [51071] (10 species)

7. Species Human (Homo sapiens), erythrocytes, isozyme II [TaxId:9606] [51073] (682 PDB entries)
   Uniprot P00918

8. Domain d3f4xa_: 3f4x A: [175472]
   automated match to d1cana_
   complexed with hg, klt, zn

Details for d3f4xa_

PDB Entry: 3f4x, 1.9 Å

PDB Description: carbonic anhydrase inhibitors. comparison of chlorthalidone and indapamide x-ray crystal structures in adducts with isozyme ii: when three water molecules make the difference

PDB Compounds: (A:) Carbonic anhydrase 2

SCOPe Domain Sequences for d3f4xa_:

Sequence; same for both SEQRES and ATOM records:

>d3f4xa_ b.74.1.1 (A:) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
ntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgl
lpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvdn
wrpaqplknrqikasf

Timeline for d3f4xa_:

• d3f4xa_ first appeared in SCOPe 2.01
  
• d3f4xa_ appears in SCOPe 2.05
  
• d3f4xa_ appears in SCOPe 2.07
  
• d3f4xa_ appears in the current release, SCOPe 2.08