SCOPe 2.02: Domain d3bvab_: 3bva B:

Lineage for d3bvab_ (3bva B:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (7 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (413 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d3bvab_: 3bva B: [172836]
   automated match to d1dw6c_
   complexed with 2nc, gol; mutant

Details for d3bvab_

PDB Entry: 3bva, 1.05 Å

PDB Description: cystal structure of hiv-1 active site mutant d25n and p2-nc analog inhibitor

PDB Compounds: (B:) Protease (Retropepsin)

SCOPe Domain Sequences for d3bvab_:

Sequence; same for both SEQRES and ATOM records:

>d3bvab_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkeallntgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

Timeline for d3bvab_:

• d3bvab_ first appeared in SCOPe 2.01
  
• d3bvab_ appears in SCOPe 2.03
  
• d3bvab_ appears in the current release, SCOPe 2.08