SCOPe 2.05: Domain d2e0ca_: 2e0c A:

Lineage for d2e0ca_ (2e0c A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.0: automated matches [191423] (1 protein)
   not a true family

6. Protein automated matches [190603] (14 species)
   not a true protein

7. Species Sulfolobus tokodaii [TaxId:273063] [187622] (3 PDB entries)

8. Domain d2e0ca_: 2e0c A: [163781]
   automated match to d1ai2a_

Details for d2e0ca_

PDB Entry: 2e0c, 2 Å

PDB Description: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii strain7 at 2.0 a resolution

PDB Compounds: (A:) 409aa long hypothetical NADP-dependent isocitrate dehydrogenase

SCOPe Domain Sequences for d2e0ca_:

Sequence, based on SEQRES records:

>d2e0ca_ c.77.1.0 (A:) automated matches {Sulfolobus tokodaii [TaxId: 273063]}
mlykepedgekikfdkgkwivpnkpvilyiegdgigpeitnaaikvinkaveraygssre
ikwlevyagekaeklvndrfpketqemllkyrvvlkgpletpigkgwksvnvairlmldl
yanirpvkyieglesplkhpekvdmiifrentddlyrgieypfnseeakkirdflrkelk
veieddtgigikvmskyktqritrlaiqyaiehkrkkvtimhkgnvmkytegafrewaye
valkeyrdfivteeeinqgkpdqgkiilndriadnmfqqiiirpeeydiilapnvngdyi
sdaagalignigmlgganigdeggmfeaihgtapkyagknvanptgiikagelmlrwmgw
neaadliekainmairdkkvtqdiarfmgvkalgtkeyadelikimdti

Sequence, based on observed residues (ATOM records):

>d2e0ca_ c.77.1.0 (A:) automated matches {Sulfolobus tokodaii [TaxId: 273063]}
mlykepedgekikfdkgkwivpnkpvilyiegdgigpeitnaaikvinkaveraygssre
ikwlevyagekaeklvndrfpketqemllkyrvvlkgplesvnvairlmldlyanirpvk
yieglesplkhpekvdmiifrentddlyrgieypfnseeakkirdflrkelkveieddtg
igikvmskyktqritrlaiqyaiehkrkkvtimhkgnvmkytegafrewayevalkeyrd
fivteeeinqgkpdqgkiilndriadnmfqqiiirpeeydiilapnvngdyisdaagali
gnigmlgganigdeggmfeaihgtapkyagknvanptgiikagelmlrwmgwneaadlie
kainmairdkkvtqdiarfmgvkalgtkeyadelikimdti

Timeline for d2e0ca_:

• d2e0ca_ first appeared in SCOPe 2.01
  
• d2e0ca_ appears in SCOPe 2.04
  
• d2e0ca_ appears in SCOPe 2.06
  
• d2e0ca_ appears in the current release, SCOPe 2.08