SCOPe 2.02: Domain d1w5xb_: 1w5x B:

Lineage for d1w5xb_ (1w5x B:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein automated matches [190433] (11 species)
   not a true protein

7. Species Human immunodeficiency virus [TaxId:12721] [188065] (4 PDB entries)

8. Domain d1w5xb_: 1w5x B: [161358]
   Other proteins in same PDB: d1w5xa_
   automated match to d1ajva_
   complexed with be5

Details for d1w5xb_

PDB Entry: 1w5x, 1.9 Å

PDB Description: hiv-1 protease in complex with fluoro substituted diol-based c2- symmetric inhibitor

PDB Compounds: (B:) Pol polyprotein

SCOPe Domain Sequences for d1w5xb_:

Sequence; same for both SEQRES and ATOM records:

>d1w5xb_ b.50.1.1 (B:) automated matches {Human immunodeficiency virus [TaxId: 12721]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d1w5xb_:

• d1w5xb_ first appeared in SCOPe 2.01
  
• d1w5xb_ appears in SCOPe 2.03
  
• d1w5xb_ appears in the current release, SCOPe 2.08