SCOPe 2.06: Domain d3cemb_: 3cem B:

Lineage for d3cemb_ (3cem B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.87: UDP-Glycosyltransferase/glycogen phosphorylase [53755] (1 superfamily)
   consists of two non-similar domains with 3 layers (a/b/a) each
   domain 1: parallel beta-sheet of 7 strands, order 3214567
   domain 2: parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.87.1: UDP-Glycosyltransferase/glycogen phosphorylase [53756] (14 families)

5. Family c.87.1.4: Oligosaccharide phosphorylase [53766] (3 proteins)
   automatically mapped to Pfam PF00343

6. Protein Glycogen phosphorylase [53767] (3 species)
   both domains are elaborated with many insertions

7. Species Human (Homo sapiens) [TaxId:9606] [53768] (16 PDB entries)

8. Domain d3cemb_: 3cem B: [156529]
   automated match to d1fc0a_
   complexed with avd, nbg, plp

Details for d3cemb_

PDB Entry: 3cem, 2.47 Å

PDB Description: human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor ave9423

PDB Compounds: (B:) Glycogen phosphorylase, liver form

SCOPe Domain Sequences for d3cemb_:

Sequence, based on SEQRES records:

>d3cemb_ c.87.1.4 (B:) Glycogen phosphorylase {Human (Homo sapiens) [TaxId: 9606]}
nvaelkksfnrhlhftlvkdrnvattrdyyfalahtvrdhlvgrwirtqqhyydkcpkrv
yylslefymgrtlqntminlglqnacdeaiyqlgldieeleeieedaglgngglgrlaac
fldsmatlglaaygygiryeygifnqkirdgwqveeaddwlrygnpweksrpefmlpvhf
ygkvehtntgtkwidtqvvlalpydtpvpgymnntvntmrlwsarapndfnlrdfnvgdy
iqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfkaskfgstrga
gtvfdafpdqvaiqlndthpalaipelmrifvdieklpwskaweltqktfaytnhtvlpe
alerwpvdlvekllprhleiiyeinqkhldrivalfpkdvdrlrrmslieeegskrinma
hlcivgshavngvakihsdivktkvfkdfselepdkfqnktngitprrwlllcnpglael
iaekigedyvkdlsqltklhsflgddvflrelakvkqenklkfsqfleteykvkinpssm
fdvqvkriheykrqllnclhvitmynrikkdpkklfvprtviiggkaapgyhmakmiikl
itsvadvvnndpmvgsklkviflenyrvslaekvipatdlseqistagteasgtgnmkfm
lngaltigtmdganvemaeeageenlfifgmriddvaaldkkgyeakeyyealpelklvi
dqidngffspkqpdlfkdiinmlfyhdrfkvfadyeayvkcqdkvsqlymnpkawntmvl
kniaasgkfssdrtikeyaqniwnvepsd

Sequence, based on observed residues (ATOM records):

>d3cemb_ c.87.1.4 (B:) Glycogen phosphorylase {Human (Homo sapiens) [TaxId: 9606]}
nvaelkksfnrhlhftlvkdrnvattrdyyfalahtvrdhlvgrwirtqqhyydkcpkrv
yylslefymgrtlqntminlglqnacdeaiyqlgldieeleeieedaglgngglgrlaac
fldsmatlglaaygygiryeygifnqkirdgwqveeaddwlrygnpweksrpefmlpvhf
ygkvehtntgtkwidtqvvlalpydtpvpgymnntvntmrlwsarapndfdyiqavldrn
laenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfkaskftvfdafpdqvaiql
ndthpalaipelmrifvdieklpwskaweltqktfaytnhtvlpealerwpvdlvekllp
rhleiiyeinqkhldrivalfpkdvdrlrrmslieeegskrinmahlcivgshavngvak
ihsdivktkvfkdfselepdkfqnktngitprrwlllcnpglaeliaekigedyvkdlsq
ltklhsflgddvflrelakvkqenklkfsqfleteykvkinpssmfdvqvkriheykrql
lnclhvitmynrikkdpkklfvprtviiggkaapgyhmakmiiklitsvadvvnndpmvg
sklkviflenyrvslaekvipatdlseqistagteasgtgnmkfmlngaltigtmdganv
emaeeageenlfifgmriddvaaldkkgyeakeyyealpelklvidqidngffspkqpdl
fkdiinmlfyhdrfkvfadyeayvkcqdkvsqlymnpkawntmvlkniaasgkfssdrti
keyaqniwnvepsd

Timeline for d3cemb_:

• d3cemb_ first appeared in SCOP 1.75, called d3cemb1
  
• d3cemb_ appears in SCOPe 2.05
  
• d3cemb_ appears in SCOPe 2.07
  
• d3cemb_ appears in the current release, SCOPe 2.08