SCOP 1.75: Domain d2z3ca1: 2z3c A:2-301

Lineage for d2z3ca1 (2z3c A:2-301)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (3 proteins)

6. Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (3 species)
   contains an extra alpha-helical domain

7. Species SARS coronavirus [TaxId:227859] [89349] (20 PDB entries)

8. Domain d2z3ca1: 2z3c A:2-301 [153983]
   automatically matched to d1q2wb_
   complexed with ace, ecq, gol, kcq, mbn

Details for d2z3ca1

PDB Entry: 2z3c, 1.79 Å

PDB Description: a mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the sars-cov 3c-like peptidase

PDB Compounds: (A:) Replicase polyprotein 1ab (pp1ab)

SCOP Domain Sequences for d2z3ca1:

Sequence; same for both SEQRES and ATOM records:

>d2z3ca1 b.47.1.4 (A:2-301) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {SARS coronavirus [TaxId: 227859]}
gfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllirk
snhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyngs
psgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegkf
ygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynyep
ltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqcs

Timeline for d2z3ca1:

• d2z3ca1 is new in SCOP 1.75
  
• d2z3ca1 is called d2z3ca_ in SCOPe 2.01
  
• d2z3ca1 appears in the current release, SCOPe 2.08, called d2z3ca_