SCOPe 2.02: Domain d2o4ga1: 2o4g A:9-234

Lineage for d2o4ga1 (2o4g A:9-234)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.5: DnaQ-like 3'-5' exonuclease [53118] (16 proteins)
   contains Pfam PF00929

6. Protein Three prime repair exonuclease 1, TREX1 [159631] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [159632] (6 PDB entries)
   Uniprot Q91XB0 5-234! Uniprot Q91XB0 9-234

8. Domain d2o4ga1: 2o4g A:9-234 [148584]
   Other proteins in same PDB: d2o4gb_, d2o4gc_, d2o4gd_
   protein/DNA complex; complexed with mg, tmp

Details for d2o4ga1

PDB Entry: 2o4g, 2.35 Å

PDB Description: Structure of TREX1 in complex with a nucleotide

PDB Compounds: (A:) Three prime repair exonuclease 1

SCOPe Domain Sequences for d2o4ga1:

Sequence, based on SEQRES records:

>d2o4ga1 c.55.3.5 (A:9-234) Three prime repair exonuclease 1, TREX1 {Mouse (Mus musculus) [TaxId: 10090]}
ghmqtlifldleatglpssrpevtelcllavhrralentsisqghpppvprpprvvdkls
lciapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcclvahngdr
ydfpllqtelarlstpspldgtfcvdsiaalkaleqasspsgngsrksyslgsiytrlyw
qaptdshtaegdvltllsicqwkpqallqwvdeharpfstvkpmyg

Sequence, based on observed residues (ATOM records):

>d2o4ga1 c.55.3.5 (A:9-234) Three prime repair exonuclease 1, TREX1 {Mouse (Mus musculus) [TaxId: 10090]}
ghmqtlifldleatglpssrpevtelcllavhrralentsisqghpppvprpprvvdkls
lciapgkacspgaseitglskaelevqgrqrfddnlaillraflqrqpqpcclvahngdr
ydfpllqtelarlstpspldgtfcvdsiaalkaleqaksyslgsiytrlywqaptdshta
egdvltllsicqwkpqallqwvdeharpfstvkpmyg

Timeline for d2o4ga1:

• d2o4ga1 first appeared in SCOP 1.75
  
• d2o4ga1 appears in SCOPe 2.01
  
• d2o4ga1 appears in SCOPe 2.03
  
• d2o4ga1 appears in the current release, SCOPe 2.08