SCOPe 2.01: Domain d2dfta_: 2dft A:

Lineage for d2dfta_ (2dft A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.2: Shikimate kinase (AroK) [52566] (2 proteins)
   similar to the nucleotide/nucleoside kinases but acts on different substrate

6. Protein Shikimate kinase (AroK) [52567] (4 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [75194] (10 PDB entries)
   Uniprot P95014

8. Domain d2dfta_: 2dft A: [131476]
   automated match to d1l4ua_
   complexed with adp, cl, mg

Details for d2dfta_

PDB Entry: 2dft, 2.8 Å

PDB Description: Structure of shikimate kinase from Mycobacterium tuberculosis complexed with ADP and Mg at 2.8 angstrons of resolution

PDB Compounds: (A:) Shikimate kinase

SCOPe Domain Sequences for d2dfta_:

Sequence, based on SEQRES records:

>d2dfta_ c.37.1.2 (A:) Shikimate kinase (AroK) {Mycobacterium tuberculosis [TaxId: 1773]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggntvrplla
gpdraekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrl

Sequence, based on observed residues (ATOM records):

>d2dfta_ c.37.1.2 (A:) Shikimate kinase (AroK) {Mycobacterium tuberculosis [TaxId: 1773]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggndraekyr
almakraplyrrvatmrvdtnrrnpgavvrhilsrl

Timeline for d2dfta_:

• d2dfta_ first appeared in SCOP 1.73, called d2dfta1
  
• d2dfta_ was called d2dfta1 in SCOP 1.75
  
• d2dfta_ appears in SCOPe 2.02
  
• d2dfta_ appears in the current release, SCOPe 2.08