SCOPe 2.01: Domain d2dfna_: 2dfn A:

Lineage for d2dfna_ (2dfn A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.2: Shikimate kinase (AroK) [52566] (2 proteins)
   similar to the nucleotide/nucleoside kinases but acts on different substrate

6. Protein Shikimate kinase (AroK) [52567] (4 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [75194] (10 PDB entries)
   Uniprot P95014

8. Domain d2dfna_: 2dfn A: [131475]
   automated match to d1l4ua_
   complexed with adp, cl, skm

Details for d2dfna_

PDB Entry: 2dfn, 1.93 Å

PDB Description: Structure of shikimate kinase from Mycobacterium tuberculosis complexed with ADP and shikimate at 1.9 angstrons of resolution

PDB Compounds: (A:) Shikimate kinase

SCOPe Domain Sequences for d2dfna_:

Sequence; same for both SEQRES and ATOM records:

>d2dfna_ c.37.1.2 (A:) Shikimate kinase (AroK) {Mycobacterium tuberculosis [TaxId: 1773]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggntvrplla
gpdraekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrl

Timeline for d2dfna_:

• d2dfna_ first appeared in SCOP 1.73, called d2dfna1
  
• d2dfna_ was called d2dfna1 in SCOP 1.75
  
• d2dfna_ appears in SCOPe 2.02
  
• d2dfna_ appears in the current release, SCOPe 2.08