SCOPe 2.06: Domain d2bnxa1: 2bnx A:133-475

Lineage for d2bnxa1 (2bnx A:133-475)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (26 families)

5. Family a.118.1.23: Diap1 N-terninal region-like [140830] (2 proteins)
   contains two consequitive Pfam domains in one superhelical segment: Pfam PF06371 and Pfam PF06367
   this is a repeat family; one repeat unit is 2bap A:217-262 found in domain

6. Protein Diaphanous protein homolog 1, Diap1 (Dia1, DRF1) [140831] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [140832] (4 PDB entries)
   Uniprot O08808 133-475! Uniprot O08808 135-435! Uniprot O08808 83-443

8. Domain d2bnxa1: 2bnx A:133-475 [128861]
   complexed with cl

Details for d2bnxa1

PDB Entry: 2bnx, 2.4 Å

PDB Description: crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (drf), mdia1

PDB Compounds: (A:) Diaphanous protein homolog 1

SCOPe Domain Sequences for d2bnxa1:

Sequence, based on SEQRES records:

>d2bnxa1 a.118.1.23 (A:133-475) Diaphanous protein homolog 1, Diap1 (Dia1, DRF1) {Mouse (Mus musculus) [TaxId: 10090]}
srsammyiqelrsglrdmhllscleslrvslnnnpvswvqtfgaeglaslldilkrlhde
keetsgnydsrnqheiirclkafmnnkfgiktmleteegilllvramdpavpnmmidaak
llsalcilpqpedmnervleamteraemdeverfqplldglksgtsialkvgclqlinal
itpaeeldfrvhirselmrlglhqvlqelreienedmkvqlcvfdeqgdedffdlkgrld
dirmemddfgevfqiilntvkdskaephflsilqhlllvrndyearpqyyklieecvsqi
vlhkngtdpdfkcrhlqidierlvdqmidktkvekseakatel

Sequence, based on observed residues (ATOM records):

>d2bnxa1 a.118.1.23 (A:133-475) Diaphanous protein homolog 1, Diap1 (Dia1, DRF1) {Mouse (Mus musculus) [TaxId: 10090]}
srsammyiqelrsglrdmhllscleslrvslnnnpvswvqtfgaeglaslldilkrlhde
keetsgnydsrnqheiirclkafmnnkfgiktmleteegilllvramdpavpnmmidaak
llsalcilpqpedmnervleamteraemdeverfqplldglksgtsialkvgclqlinal
itpaeeldfrvhirselmrlglhqvlqelreienedmkvqlcvfdeqgdedffdlkgrld
dirmemddfgevfqiilntvkdskaephflsilqhlllvrndyearpqyyklieecvsqi
vlhkngtdpdfkcrhlqidierlvktkvekseakatel

Timeline for d2bnxa1:

• d2bnxa1 first appeared in SCOP 1.73
  
• d2bnxa1 appears in SCOPe 2.05
  
• d2bnxa1 appears in SCOPe 2.07
  
• d2bnxa1 appears in the current release, SCOPe 2.08