SCOPe 2.05: Domain d1z4qa_: 1z4q A:

Lineage for d1z4qa_ (1z4q A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.108: HAD-like [56783] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.108.1: HAD-like [56784] (26 families)
   usually contains an insertion (sub)domain after strand 1

5. Family c.108.1.8: 5'(3')-deoxyribonucleotidase (dNT-2) [82382] (2 proteins)
   the insertion subdomain is a 4-helical bundle; dephosphorylates dUMP and dTMP
   automatically mapped to Pfam PF06941

6. Protein automated matches [190171] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186899] (17 PDB entries)

8. Domain d1z4qa_: 1z4q A: [124443]
   automated match to d1q92a_
   complexed with d4m, mg

Details for d1z4qa_

PDB Entry: 1z4q, 2.05 Å

PDB Description: structure of the d41n variant of the human mitochondrial deoxyribonucleotidase in complex with 2',3'-dideoxy-2',3- didehydrothymidine 5'-monophosphate (d4t-mp)

PDB Compounds: (A:) 5'(3')-deoxyribonucleotidase

SCOPe Domain Sequences for d1z4qa_:

Sequence; same for both SEQRES and ATOM records:

>d1z4qa_ c.108.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ralrvlvnmdgvladfeggflrkfrarfpdqpfialedrrgfwvseqygrlrpglsekai
siwesknfffeleplpgaveavkemaslqntdvfictspikmfkycpyekyawvekyfgp
dfleqivltrdktvvsadlliddrpditgaeptpswehvlftachnqhlqlqpprrrlhs
waddwkaildskrp

Timeline for d1z4qa_:

• d1z4qa_ first appeared in SCOP 1.73, called d1z4qa1
  
• d1z4qa_ appears in SCOPe 2.04
  
• d1z4qa_ appears in SCOPe 2.06
  
• d1z4qa_ appears in the current release, SCOPe 2.08