SCOPe 2.06: Domain d1s5ja1: 1s5j A:40-449

Lineage for d1s5ja1 (1s5j A:40-449)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.5: DnaQ-like 3'-5' exonuclease [53118] (17 proteins)
   contains Pfam PF00929

6. Protein Exonuclease domain of family B DNA polymerases [53125] (8 species)
   elaborated with additional structures and the N-terminal subdomain

7. Species Sulfolobus solfataricus [TaxId:2287] [117647] (1 PDB entry)
   Uniprot P26811 40-864

8. Domain d1s5ja1: 1s5j A:40-449 [112040]
   Other proteins in same PDB: d1s5ja2
   complexed with mg, so4

Details for d1s5ja1

PDB Entry: 1s5j, 2.4 Å

PDB Description: Insight in DNA Replication: The crystal structure of DNA Polymerase B1 from the archaeon Sulfolobus solfataricus

PDB Compounds: (A:) DNA polymerase I

SCOPe Domain Sequences for d1s5ja1:

Sequence, based on SEQRES records:

>d1s5ja1 c.55.3.5 (A:40-449) Exonuclease domain of family B DNA polymerases {Sulfolobus solfataricus [TaxId: 2287]}
ewleeaqenkiyfllqvdydgkkgkavcklfdketqkiyalydntghkpyflvdlepdkv
gkipkivrdpsfdhietvskidpytwnkfkltkivvrdplavrrlrndvpkayeahikyf
nnymydiglipgmpyvvkngklesvylsldekdveeikkafadsdemtrqmavdwlpife
teipkikrvaidievytpvkgripdsqkaefpiisialagsdglkkvlvlnrndvnegsv
kldgisverfnteyellgrffdilleypivltfngddfdlpyiyfralklgyfpeeipid
vagkdeakylaglhidlykfffnkavrnyafegkyneynldavakallgtskvkvdtlis
fldveklieynfrdaeitlqlttfnndltmklivlfsrisrlgieeltrt

Sequence, based on observed residues (ATOM records):

>d1s5ja1 c.55.3.5 (A:40-449) Exonuclease domain of family B DNA polymerases {Sulfolobus solfataricus [TaxId: 2287]}
ewleeaqenkiyfllqvdydgkkgkavcklfdketqkiyalydntghkpyflvdlepdkv
gkipkivrdpsfdhietvskidpytwnkfkltkivvrdplavrrlrndvpkayeahikyf
nnymydiglipgmpyvvkngklesvylsldekdveeikkafadsdemtrqmavdwlpife
teipkikrvaidievytpvkgripdsqkaefpiisialagsdglkkvlvlnrndvnegsv
kldgisverfnteyellgrffdilleypivltfngddfdlpyiyfralklgyfpeeipid
vagkdeakylaglhidlykfffnkavrnyafegkyneynldavakallgtskvdtlisfl
dveklieynfrdaeitlqlttfnndltmklivlfsrisrlgieeltrt

Timeline for d1s5ja1:

• d1s5ja1 first appeared in SCOP 1.71
  
• d1s5ja1 appears in SCOPe 2.05
  
• d1s5ja1 appears in SCOPe 2.07
  
• d1s5ja1 appears in the current release, SCOPe 2.08