SCOPe 2.02: Domain d1taza_: 1taz A:

Lineage for d1taza_ (1taz A:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase 1b, PDE1B [109944] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109945] (1 PDB entry)
   Uniprot Q01064 126-482

8. Domain d1taza_: 1taz A: [106734]
   complexed with mg, zn

Details for d1taza_

PDB Entry: 1taz, 1.77 Å

PDB Description: Catalytic Domain Of Human Phosphodiesterase 1B

PDB Compounds: (A:) Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

SCOPe Domain Sequences for d1taza_:

Sequence, based on SEQRES records:

>d1taza_ a.211.1.2 (A:) Catalytic domain of cyclic nucleotide phosphodiesterase 1b, PDE1B {Human (Homo sapiens) [TaxId: 9606]}
vgptystavlnclknldlwcfdvfslnqaaddhalrtivfelltrhnlisrfkiptvflm
sfldaletgygkyknpyhnqihaadvtqtvhcfllrtgmvhclseiellaiifaaaihdy
ehtgttnsfhiqtksecaivyndrsvlenhhissvfrlmqddemnifinltkdefvelra
lviemvlatdmschfqqvktmktalqqleridkpkalslllhaadishptkqwlvhsrwt
kalmeeffrqgdkeaelglpfsplcdrtstlvaqsqigfidfiveptfsvltdvaeksvq
pladedsksknqpsfqwrqpsldvevgdpnpdvvsfrstwvkriqenkqkwkeraas

Sequence, based on observed residues (ATOM records):

>d1taza_ a.211.1.2 (A:) Catalytic domain of cyclic nucleotide phosphodiesterase 1b, PDE1B {Human (Homo sapiens) [TaxId: 9606]}
vgptystavlnclknldlwcfdvfslnqaaddhalrtivfelltrhnlisrfkiptvflm
sfldaletgygkyknpyhnqihaadvtqtvhcfllrtgmvhclseiellaiifaaaihdy
ehtgttnsfhiqtksecaivyndrsvlenhhissvfrlmqddemnifinltkdefvelra
lviemvlatdmschfqqvktmktalqqridkpkalslllhaadishptkqwlvhsrwtka
lmeeffrqgdkeaelglprtstlvaqsqigfidfiveptfsvltdvaeksvqdpnpdvvs
frstwvkriqenkqkwkeraas

Timeline for d1taza_:

• d1taza_ first appeared in SCOP 1.69
  
• d1taza_ appears in SCOPe 2.01
  
• d1taza_ appears in SCOPe 2.03
  
• d1taza_ appears in the current release, SCOPe 2.08