Class c: Alpha and beta proteins (a/b) [51349] (147 folds) |
Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily) 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest |
Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) |
Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins) |
Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain [53610] (2 species) |
Species Cryptosporidium hominis [TaxId:237895] [102636] (3 PDB entries) Uniprot Q5CGA3 Q27552 |
Domain d1qzfa1: 1qzf A:3-180 [96633] Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2 complexed with cb3, fol, ndp, ump |
Domain d1qzfb1: 1qzf B:3-180 [96635] Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2 complexed with cb3, fol, ndp, ump |
Domain d1qzfc1: 1qzf C:3-180 [96637] Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2 complexed with cb3, fol, ndp, ump |
Domain d1qzfd1: 1qzf D:3-180 [96639] Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2 complexed with cb3, fol, ndp, ump |
Domain d1qzfe1: 1qzf E:3-180 [96641] Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2 complexed with cb3, fol, ndp, ump |
Domain d1seja1: 1sej A:3-180 [105455] Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2 complexed with f89, ndp, ump |
Domain d1sejb1: 1sej B:3-180 [105457] Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2 complexed with f89, ndp, ump |
Domain d1sejc1: 1sej C:3-180 [105459] Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2 complexed with f89, ndp, ump |
Domain d1sejd1: 1sej D:3-180 [105461] Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2 complexed with f89, ndp, ump |
Domain d1seje1: 1sej E:3-180 [105463] Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2 complexed with f89, ndp, ump |
Domain d2oipa1: 2oip A:3-180 [148784] Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2 automatically matched to d1qzfa1 complexed with cb3, mtx, ndp, ump; mutant |
Domain d2oipb1: 2oip B:3-180 [148786] Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2 automatically matched to d1qzfa1 complexed with cb3, mtx, ndp, ump; mutant |
Domain d2oipc1: 2oip C:3-180 [148788] Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2 automatically matched to d1qzfa1 complexed with cb3, mtx, ndp, ump; mutant |
Domain d2oipd1: 2oip D:3-180 [148790] Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2 automatically matched to d1qzfa1 complexed with cb3, mtx, ndp, ump; mutant |
Domain d2oipe1: 2oip E:3-180 [148792] Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2 automatically matched to d1qzfa1 complexed with cb3, mtx, ndp, ump; mutant |
Timeline for Species Cryptosporidium hominis [TaxId:237895] from c.71.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain: