PDB entry 7ya1

View 7ya1 on RCSB PDB site
Description: Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (local refinement)
Class: hydrolase/viral protein
Keywords: SARS-CoV-2, Omicron, spike protein, VIRAL PROTEIN, HYDROLASE-VIRAL PROTEIN complex
Deposited on 2022-06-27, released 2022-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-09-07, with a file datestamp of 2022-09-02.
Experiment type: EM
Resolution: 3.11 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Angiotensin-converting enzyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7ya1a_
  • Chain 'B':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (0-194)
      • variant (6)
      • variant (84)
      • variant (107)
      • variant (113)
      • variant (144-145)
      • variant (151)
      • variant (160)
      • variant (163)
      • variant (165)
      • variant (168)
      • variant (172)
    Domains in SCOPe 2.08: d7ya1b_
  • Heterogens: NAG, ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7ya1A (A:)
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspya

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7ya1B (B:)
tnlcpfdevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcf
tnvyadsfvirgdevrqiapgqtgniadynyklpddftgcviawnsnkldskvsgnynyl
yrlfrksnlkpferdisteiyqagnkpcngvagfncyfplrsysfrptygvghqpyrvvv
lsfellhapatvcgp