PDB entry 7qq5

View 7qq5 on RCSB PDB site
Description: Structure of CTX-M-15 K73A mutant crystallised in the presence of enmetazobactam (AAI101)
Class: antimicrobial protein
Keywords: beta-lactamase, inhibitor, antibiotic resistance, cross-link, ANTIMICROBIAL PROTEIN
Deposited on 2022-01-06, released 2022-05-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-07-06, with a file datestamp of 2022-07-01.
Experiment type: XRAY
Resolution: 0.95 Å
R-factor: N/A
AEROSPACI score: 0.97 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1EPV7 (2-264)
      • expression tag (0-1)
      • conflict (46)
      • engineered mutation (49)
    Domains in SCOPe 2.08: d7qq5a_
  • Heterogens: DSN, SO4, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7qq5A (A:)
gpqtadvqqklaelerqsggrlgvalintadnsqilyraderfamcstsavmaaaavlkk
sesepnllnqrveikksdlvnynpiaekhvngtmslaelsaaalqysdnvamnkliahvg
gpasvtafarqlgdetfrldrteptlntaipgdprdttspramaqtlrnltlgkalgdsq
raqlvtwmkgnttgaasiqaglpaswvvgdktgsggygttndiaviwpkdraplilvtyf
tqpqpkaesrrdvlasaakivtdgl

    Sequence, based on observed residues (ATOM records): (download) 
    >7qq5A (A:)
advqqklaelerqsggrlgvalintadnsqilyraderfamcstsavmaaaavlkksese
pnllnqrveikksdlvnynpiaekhvngtmslaelsaaalqysdnvamnkliahvggpas
vtafarqlgdetfrldrteptlntaipgdprdttspramaqtlrnltlgkalgdsqraql
vtwmkgnttgaasiqaglpaswvvgdktgsggygttndiaviwpkdraplilvtyftqpq
pkaesrrdvlasaakivtd