PDB entry 7np0

View 7np0 on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis ArgF in complex with (4-nitrophenyl)boronic acid.
Class: transferase
Keywords: ArgF, Ornithine Carbamoyltransferase, TRANSFERASE
Deposited on 2021-02-26, released 2021-06-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (1-2)
    Domains in SCOPe 2.08: d7np0a1, d7np0a2, d7np0a3
  • Chain 'B':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (2)
    Domains in SCOPe 2.08: d7np0b1, d7np0b2, d7np0b3
  • Chain 'C':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (2)
    Domains in SCOPe 2.08: d7np0c1, d7np0c2, d7np0c3
  • Chain 'D':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (2)
    Domains in SCOPe 2.08: d7np0d1, d7np0d2, d7np0d3
  • Chain 'E':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (2)
    Domains in SCOPe 2.08: d7np0e1, d7np0e2, d7np0e3
  • Chain 'F':
    Compound: ornithine carbamoyltransferase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: argF, Rv1656, MTCY06H11.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WIT9 (3-308)
      • expression tag (1-2)
    Domains in SCOPe 2.08: d7np0f1, d7np0f2, d7np0f3
  • Heterogens: UKH, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7np0A (A:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7np0A (A:)
svirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfel
giaqlgghavvvdsglgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvina
lsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaape
gflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldrvkpf
rpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvw
llers

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7np0B (B:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7np0B (B:)
virhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfelg
iaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvi
nalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaa
pegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtdrvkpfrpfqlns
rllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvwllers

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7np0C (C:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7np0C (C:)
virhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfelg
iaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvi
nalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaa
pegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldrvk
pfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkall
vwllers

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7np0D (D:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7np0D (D:)
virhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfelg
iaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvi
nalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaa
pegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtdrvkpfrpfqlns
rllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvwllers

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7np0E (E:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7np0E (E:)
virhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfelg
iaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpvi
nalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtvaa
pegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtldrvkpfrpfqln
srllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvwllers

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7np0F (F:)
gsvirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfe
lgiaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvp
vinalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtv
aapegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtsmgqendgldr
vkpfrpfqlnsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqka
llvwllers

    Sequence, based on observed residues (ATOM records): (download) 
    >7np0F (F:)
svirhflrdddlspaeqaevlelaaelkkdpvsrrplqgprgvavifdknstrtrfsfel
giaqlgghavvvdsgstqlgrdetlqdtakvlsryvdaivwrtfgqerldamasvatvpv
inalsdefhpcqvladlqtiaerkgalrglrlsyfgdgannmahslllggvtagihvtva
apegflpdpsvraaaerraqdtgasvtvtadahaaaagadvlvtdtwtldrvkpfrpfql
nsrllaladsdaivlhclpahrgdeitdavmdgpasavwdeaenrlhaqkallvwllers