PDB entry 7n7o

View 7n7o on RCSB PDB site
Description: Crystal Structure of PI5P4KIIAlpha complex with Palbociclib
Class: transferase/transferase inhibitor
Keywords: kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2021-06-10, released 2021-06-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PIP4K2A, PI5P4KA, PIP5K2, PIP5K2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48426 (4-376)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d7n7oa_
  • Heterogens: LQQ, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7n7oA (A:)
gshmasdpllsvlmwgvnhsinelshvqipvmlmpddfkayskikvdnhlfnkenmpshf
kfkeycpmvfrnlrerfgiddqdfqnsltrsaplpndsqarsgarfhtsydkryiiktit
sedvaemhnilkkyhqyivechgitllpqflgmyrlnvdgveiyvivtrnvfshrlsvyr
kydlkgstvareasdkekakelptlkdndfinegqkiyiddnnkkvfleklkkdveflaq
lklmdysllvgihdveraeqeeveceendgeeegesdgthpvgtppdspgntlnssppla
pgefdpnidvygikchensprkevyfmaiidilthydakkkaahaaktvkhgagaeistv
npeqyskrfldfighil

    Sequence, based on observed residues (ATOM records): (download) 
    >7n7oA (A:)
sdpllsvlmwgvnhsinelshvqipvmlmpddfkayskikvdnhlfnkenmpshfkfkey
cpmvfrnlrerfgiddqdfqnsltrsaplpndsrfhtsydkryiiktitsedvaemhnil
kkyhqyivechgitllpqflgmyrlnvdgveiyvivtrnvfshrlsvyrkydlkgstvar
easdkekakelptlkdndfinegqkiyiddnnkkvfleklkkdveflaqlklmdysllvg
ihdveralapgefdpnidvygikchensprkevyfmaiidilthvnpeqyskrfldfigh
il