PDB entry 7lxy

View 7lxy on RCSB PDB site
Description: SARS-CoV-2 S/S2M11/S2X333 Global Refinement
Class: viral protein/immune system
Keywords: Antibody, VIRAL PROTEIN, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, SSGCID, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2021-03-05, released 2021-04-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-12, with a file datestamp of 2021-05-07.
Experiment type: EM
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (816)
      • engineered mutation (891)
      • engineered mutation (898)
      • engineered mutation (941)
      • engineered mutation (985-986)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (816)
      • engineered mutation (891)
      • engineered mutation (898)
      • engineered mutation (941)
      • engineered mutation (985-986)
  • Chain 'C':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-103)
    Domains in SCOPe 2.08: d7lxyc_
  • Chain 'D':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-103)
    Domains in SCOPe 2.08: d7lxyd_
  • Chain 'E':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-121)
    Domains in SCOPe 2.08: d7lxye_
  • Chain 'F':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-121)
    Domains in SCOPe 2.08: d7lxyf_
  • Chain 'G':
    Compound: S2X333 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-120)
    Domains in SCOPe 2.08: d7lxyg_
  • Chain 'H':
    Compound: S2X333 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-120)
    Domains in SCOPe 2.08: d7lxyh_
  • Chain 'I':
    Compound: S2X333 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-99)
    Domains in SCOPe 2.08: d7lxyi_
  • Chain 'J':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (816)
      • engineered mutation (891)
      • engineered mutation (898)
      • engineered mutation (941)
      • engineered mutation (985-986)
  • Chain 'K':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-103)
    Domains in SCOPe 2.08: d7lxyk_
  • Chain 'L':
    Compound: S2X333 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-99)
    Domains in SCOPe 2.08: d7lxyl_
  • Chain 'M':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-121)
    Domains in SCOPe 2.08: d7lxym_
  • Chain 'N':
    Compound: S2X333 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-120)
    Domains in SCOPe 2.08: d7lxyn_
  • Chain 'O':
    Compound: S2X333 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXY (0-99)
    Domains in SCOPe 2.08: d7lxyo_
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyC (C:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyD (D:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyE (E:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyF (F:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyG (G:)
vqlvesgggvvqpgrslrlscaasgftfsnygmhwvrqapgkglewvaviwydgsnkfya
dsvkgrftisrdnsknslylqmnslraedtavyfcarafpdssswsgftidywgqgtlvt
v

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyH (H:)
vqlvesgggvvqpgrslrlscaasgftfsnygmhwvrqapgkglewvaviwydgsnkfya
dsvkgrftisrdnsknslylqmnslraedtavyfcarafpdssswsgftidywgqgtlvt
v

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyI (I:)
yeltqppsvstaritcggnnierksvhwcqqkpgqapalvvyddsdrpsgiperfsgsns
gntatltisrveagdeadyycqvwdsgsdqvifgggtklt

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyK (K:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyL (L:)
yeltqppsvstaritcggnnierksvhwcqqkpgqapalvvyddsdrpsgiperfsgsns
gntatltisrveagdeadyycqvwdsgsdqvifgggtklt

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyM (M:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyN (N:)
vqlvesgggvvqpgrslrlscaasgftfsnygmhwvrqapgkglewvaviwydgsnkfya
dsvkgrftisrdnsknslylqmnslraedtavyfcarafpdssswsgftidywgqgtlvt
v

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxyO (O:)
yeltqppsvstaritcggnnierksvhwcqqkpgqapalvvyddsdrpsgiperfsgsns
gntatltisrveagdeadyycqvwdsgsdqvifgggtklt