PDB entry 7kmi

View 7kmi on RCSB PDB site
Description: LY-CoV481 neutralizing antibody against SARS-CoV-2
Class: immune system/viral protein
Keywords: antibody neutralizing SARS-CoV-2, IMMUNE SYSTEM, IMMUNE SYSTEM-VIRAL PROTEIN complex
Deposited on 2020-11-02, released 2021-01-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-01-27, with a file datestamp of 2021-01-22.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: LY-CoV481 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KMI (0-End)
  • Chain 'B':
    Compound: LY-CoV481 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KMI (0-212)
    Domains in SCOPe 2.07: d7kmib1, d7kmib2
  • Chain 'C':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (Start-198)
      • expression tag (199-200)
    Domains in SCOPe 2.07: d7kmic1, d7kmic2
  • Heterogens: GOL, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7kmiB (B:)
diqmtqspssvsasvgdrvtitcrasqgisswlawyqqkpgkapklliyaasslqsgvps
rfsgsgsgtdftltisslqpedfatyycqqansfpggtfgpgtkvdikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevtqgttsvtksfnrgec

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7kmiC (C:)
fpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkln
dlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggn
ynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpy
rvvvlsfellhapatvcgphhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7kmiC (C:)
nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcft
nvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynyly
rlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvvl
sfellhapatvcgphh