PDB entry 7kfi

View 7kfi on RCSB PDB site
Description: SARS-CoV-2 Main protease immature form - apo structure
Class: hydrolase
Keywords: 3cl, protease, sars, sars-cov-2, covid, main protease, HYDROLASE
Deposited on 2020-10-14, released 2020-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-308)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7kfia1, d7kfia2
  • Chain 'B':
    Compound: 3C-like proteinase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-308)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7kfib_
  • Heterogens: DMS, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kfiA (A:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcsgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >7kfiA (A:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7kfiB (B:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcsgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >7kfiB (B:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllir
ksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegn
fygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqc
s