PDB entry 7k1o

View 7k1o on RCSB PDB site
Description: Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with Uridine-3',5'-Diphosphate
Class: viral protein
Keywords: SARS Corona virus 2, endoribonuclease, COVID-19, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, VIRAL PROTEIN
Deposited on 2020-09-08, released 2020-09-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-23, with a file datestamp of 2020-09-18.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (24-End)
      • expression tag (23)
    Domains in SCOPe 2.07: d7k1oa1, d7k1oa2, d7k1oa3
  • Chain 'B':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (24-End)
      • expression tag (22-23)
    Domains in SCOPe 2.07: d7k1ob1, d7k1ob2, d7k1ob3
  • Chain 'C':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (24-End)
      • expression tag (22-23)
    Domains in SCOPe 2.07: d7k1oc1, d7k1oc2, d7k1oc3
  • Heterogens: VQV, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7k1oA (A:)
mhhhhhhssgvdlgtenlyfqsnmslenvafnvvnkghfdgqqgevpvsiinntvytkvd
gvdvelfenkttlpvnvafelwakrnikpvpevkilnnlgvdiaantviwdykrdapahi
stigvcsmtdiakkpteticapltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvg
pkqaslngvtligeavktqfnyykkvdgvvqqlpetyftqsrnlqefkprsqmeidflel
amdefieryklegyafehivygdfshsqlgglhlliglakrfkespfeledfipmdstvk
nyfitdaqtgsskcvcsvidlllddfveiiksqdlsvvskvvkvtidyteisfmlwckdg
hvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >7k1oA (A:)
mslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelwa
krnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticapl
tvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfnyy
kkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivygd
fshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidlll
ddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7k1oB (B:)
mhhhhhhssgvdlgtenlyfqsnmslenvafnvvnkghfdgqqgevpvsiinntvytkvd
gvdvelfenkttlpvnvafelwakrnikpvpevkilnnlgvdiaantviwdykrdapahi
stigvcsmtdiakkpteticapltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvg
pkqaslngvtligeavktqfnyykkvdgvvqqlpetyftqsrnlqefkprsqmeidflel
amdefieryklegyafehivygdfshsqlgglhlliglakrfkespfeledfipmdstvk
nyfitdaqtgsskcvcsvidlllddfveiiksqdlsvvskvvkvtidyteisfmlwckdg
hvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >7k1oB (B:)
nmslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypkl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7k1oC (C:)
mhhhhhhssgvdlgtenlyfqsnmslenvafnvvnkghfdgqqgevpvsiinntvytkvd
gvdvelfenkttlpvnvafelwakrnikpvpevkilnnlgvdiaantviwdykrdapahi
stigvcsmtdiakkpteticapltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvg
pkqaslngvtligeavktqfnyykkvdgvvqqlpetyftqsrnlqefkprsqmeidflel
amdefieryklegyafehivygdfshsqlgglhlliglakrfkespfeledfipmdstvk
nyfitdaqtgsskcvcsvidlllddfveiiksqdlsvvskvvkvtidyteisfmlwckdg
hvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >7k1oC (C:)
nmslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypkl