PDB entry 7b2y
View 7b2y on RCSB PDB site
Description: Notum complex with ARUK3003910
Class: hydrolase
Keywords: Notum Inhibitor, HYDROLASE
Deposited on
2020-11-28, released
2021-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated
2021-08-25, with a file datestamp of
2021-08-20.
Experiment type: XRAY
Resolution: 1.23 Å
R-factor: N/A
AEROSPACI score: 0.71
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Palmitoleoyl-protein carboxylesterase NOTUM
Species: Homo sapiens [TaxId:9606]
Gene: NOTUM, OK/SW-CL.30
Database cross-references and differences (RAF-indexed):
- Uniprot Q6P988 (3-373)
- expression tag (0-2)
- engineered mutation (252)
- expression tag (374-382)
Domains in SCOPe 2.08: d7b2ya1, d7b2ya2 - Heterogens: SRQ, NAG, SO4, DMS, EDO, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>7b2yA (A:)
etgsaqqlnedlrlhlllntsvtcndgspagyylkesrgsrrwllfleggwycfnrencd
srydtmrrlmssrdwprtrtgtgilssqpeenpywwnanmvfipycssdvwsgassksek
neyafmgaliiqevvrellgrglsgakvlllagssaggtgvllnvdrvaeqleklgypai
qvrgladsgwfldnkqyrhtdcvdtitcapteairrgirywngvvpercrrqfqegeewn
cffgykvyptlrspvfvvqwlfdeaqltvdnvhltgqpvqeglrlyiqnlgrelrhtlkd
vpasfapaclsheiiirshwtdvqvkgtslpralhcwdrslhdshkasktplkgcpvhlv
dscpwphcnpscptgtkhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>7b2yA (A:)
edlrlhlllntsvtcndgspagyylkesrgsrrwllfleggwycfnrencdsrydtmrrl
mssrdwprtrtgtgilssqpeenpywwnanmvfipycssdvwsgassksekneyafmgal
iiqevvrellgrglsgakvlllagssaggtgvllnvdrvaeqleklgypaiqvrgladsg
wfldnkqyrhtdcvdtitcapteairrgirywngvvpercrrqfqegeewncffgykvyp
tlrspvfvvqwlfdeaqltvdnvhlpvqeglrlyiqnlgrelrhtlkdvpasfapaclsh
eiiirshwtdvqvkgtslpralhcwdrslhplkgcpvhlvdscpwphcnpscptg