PDB entry 6yoj

View 6yoj on RCSB PDB site
Description: FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one
Class: transferase
Keywords: protein tyrosine kinase, ATP binding, transferase, transferase-inhibitor complex
Deposited on 2020-04-14, released 2021-02-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: N/A
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Focal adhesion kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PTK2, FAK, FAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6yoja_
  • Heterogens: P4N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6yojA (A:)
gsgstrdyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrek
flqealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilya
yqlstalayleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpik
wmapesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppnc
pptlyslmtkcwaydpsrrprftelkaqlstileeekaqqee

    Sequence, based on observed residues (ATOM records): (download) 
    >6yojA (A:)
dyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqeal
tmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlsta
layleskrfvhrdiaarnvlvssndcvklgdfglsrlpikwmapesinfrrftsasdvwm
fgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrp
rftelkaqlstileeekaq