PDB entry 6wnh

View 6wnh on RCSB PDB site
Description: Menin bound to inhibitor M-808
Class: transcription
Keywords: Inhibitor, PROTEIN BINDING, TRANSCRIPTION
Deposited on 2020-04-22, released 2020-05-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Menin
    Species: Homo sapiens [TaxId:9606]
    Gene: MEN1, SCG2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6wnha1, d6wnha2
  • Heterogens: 7MM, 7PR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wnhA (A:)
sglkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrviptnvpe
ltfqpspapdppggltyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkk
vsdviwnslsrsyfkdrahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsed
hawvvfgpngeqtaevtwhgkgnedrrgqtvnagvaerswlylkgsymrcdrkmevafmv
cainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleeleptpgrpdplt
lyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqdynycredeei
ykeffevandvipnllkeaaslleageerpgeqsqgtqsqgsalqdpecfahllrfydgi
ckweegsptpvlhvgwatflvqslgrfegqvrqkvrivsgtvagtargpeggstaqvpap
taspppegpvltfqsekmkgmkellvatkinssaiklqltaqsqvqmkkqkvstpsdytl
sflkrqrkgl

    Sequence, based on observed residues (ATOM records): (download) 
    >6wnhA (A:)
glkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrviptnvpel
tfqpspapdgltyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdv
iwnslsrsyfkdrahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsedhawv
vfgpngeqtaevtwhgkgnedrrgqtvnagvaerswlylkgsymrcdrkmevafmvcain
psidlhtdslellqlqqkllwllydlghlerypmalgnladleeleptpgrpdpltlyhk
giasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqdynycredeeiykef
fevandvipnllkeaaslleasalqdpecfahllrfydgickweegsptpvlhvgwatfl
vqslgrfegqvrqkvrivsgtvagtargpvltfqsekmkgmkellvatkinssaiklqlt
a