PDB entry 6ti9

View 6ti9 on RCSB PDB site
Description: Human transthyretin (TTR) complexed with (E)-3-(((3,5-dibromo-2-hydroxybenzylidene)amino)oxy)propanoic acid.
Class: protein transport
Keywords: Transthyretin, TTR, inhibitor, complex, PROTEIN TRANSPORT
Deposited on 2019-11-22, released 2020-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ti9a_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ti9b_
  • Heterogens: ND5, GOL, PGO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ti9A (A:)
ggptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglt
teeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystt
avvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6ti9A (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ti9B (B:)
ggptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglt
teeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystt
avvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6ti9B (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn