PDB entry 6hm0

View 6hm0 on RCSB PDB site
Description: Crystal structure of human BRD9 bromodomain in complex with a PROTAC
Class: transcription
Keywords: protac, lysine-acetylated histone binding, chromatin regulator, transcription
Deposited on 2018-09-11, released 2019-01-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-16, with a file datestamp of 2019-01-11.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 9
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD9, UNQ3040/PRO9856
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6hm0a_
  • Chain 'B':
    Compound: Bromodomain-containing protein 9
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD9, UNQ3040/PRO9856
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6hm0b_
  • Heterogens: GBW, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hm0A (A:)
smlklsaenestpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmk
dkivaneyksvtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkr
sms

    Sequence, based on observed residues (ATOM records): (download) 
    >6hm0A (A:)
stpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkivaneyks
vtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkrsm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6hm0B (B:)
smlklsaenestpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmk
dkivaneyksvtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkr
sms

    Sequence, based on observed residues (ATOM records): (download) 
    >6hm0B (B:)
stpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkivaneyks
vtefkadfklmcdnamtynrpdtvyyklakkilhagfkmmskerllalkrsm