PDB entry 6c07

View 6c07 on RCSB PDB site
Description: Crystal Structure of S-Adenosylmethionine synthetase (MetK/Mat) from Cryptosporidium parvum
Class: transferase
Keywords: S-Adenosylmethionine synthetase, Enzyme metabolism, Anti-infective target, Anti-cancer target, TRANSFERASE
Deposited on 2017-12-28, released 2019-01-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-16, with a file datestamp of 2019-01-11.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-adenosylmethionine synthase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd7_2650
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c07a1, d6c07a2, d6c07a3
  • Chain 'B':
    Compound: S-adenosylmethionine synthase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd7_2650
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c07b1, d6c07b2, d6c07b3
  • Chain 'C':
    Compound: S-adenosylmethionine synthase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd7_2650
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c07c1, d6c07c2, d6c07c3
  • Chain 'D':
    Compound: S-adenosylmethionine synthase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd7_2650
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6c07d1, d6c07d2, d6c07d3
  • Heterogens: CL, MG, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6c07A (A:)
mdssrfsgnkstytdlqttseqflfssesvcsghpdklcdqisdaildacleqdpesfva
cetctktgfimvfgeittkanvnyervvretvkeigydseekgldyktmdviikleqqsn
qiagcvhvdknvedigagdqgmmfgyatnetkelmplthvlatsitreldyirvkgvssr
vgwlrpdgkaqvtveynckhgvlipkrihtilvsvqhdenieneeirefvlenvikkvcp
sdlmdketrilinpsgrftiggpaadagltgrkiivdtyggwgahgggafsgkdatkvdr
sgaymarlvaksivfsglcsrclvqvsygigiarplslyintfgtakdgyndaklleivn
kvfdfrpgilikqlnlkspifkktssgghfgrseeeflwekpiilq

    Sequence, based on observed residues (ATOM records): (download) 
    >6c07A (A:)
eqflfssesvcsghpdklcdqisdaildacleqdpesfvacetctktgfimvfgeittka
nvnyervvretvkeigydseekgldyktmdviikleqqdknvedigagdqgmmfgyatne
tkelmplthvlatsitreldyirvkgvssrvgwlrpdgkaqvtveynckhgvlipkriht
ilvsvqhdenieneeirefvlenvikkvcpsdlmdketrilinpsgrftiggpaadaglt
grkiivdtyggwgahgggafsgkdatkvdrsgaymarlvaksivfsglcsrclvqvsygi
giarplslyintfgtakdgyndaklleivnkvfdfrpgilikqlnlkspifkktssgghf
grseeeflwekpiilq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6c07B (B:)
mdssrfsgnkstytdlqttseqflfssesvcsghpdklcdqisdaildacleqdpesfva
cetctktgfimvfgeittkanvnyervvretvkeigydseekgldyktmdviikleqqsn
qiagcvhvdknvedigagdqgmmfgyatnetkelmplthvlatsitreldyirvkgvssr
vgwlrpdgkaqvtveynckhgvlipkrihtilvsvqhdenieneeirefvlenvikkvcp
sdlmdketrilinpsgrftiggpaadagltgrkiivdtyggwgahgggafsgkdatkvdr
sgaymarlvaksivfsglcsrclvqvsygigiarplslyintfgtakdgyndaklleivn
kvfdfrpgilikqlnlkspifkktssgghfgrseeeflwekpiilq

    Sequence, based on observed residues (ATOM records): (download) 
    >6c07B (B:)
qflfssesvcsghpdklcdqisdaildacleqdpesfvacetctktgfimvfgeittkan
vnyervvretvkeigydseekgldyktmdviikleqqknvedigagdqgmmfgyatnetk
elmplthvlatsitreldyirvkgwlrpdgkaqvtveynckhgvlipkrihtilvsvqhd
enieneeirefvlenvikkvcpsdlmdketrilinpsgrftiggpaadagltgrkiivdt
yggwgahgggafsgkdatkvdrsgaymarlvaksivfsglcsrclvqvsygigiarplsl
yintfgtakdgyndaklleivnkvfdfrpgilikqlnlkspifkktssgghfgrseeefl
wekpiilq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6c07C (C:)
mdssrfsgnkstytdlqttseqflfssesvcsghpdklcdqisdaildacleqdpesfva
cetctktgfimvfgeittkanvnyervvretvkeigydseekgldyktmdviikleqqsn
qiagcvhvdknvedigagdqgmmfgyatnetkelmplthvlatsitreldyirvkgvssr
vgwlrpdgkaqvtveynckhgvlipkrihtilvsvqhdenieneeirefvlenvikkvcp
sdlmdketrilinpsgrftiggpaadagltgrkiivdtyggwgahgggafsgkdatkvdr
sgaymarlvaksivfsglcsrclvqvsygigiarplslyintfgtakdgyndaklleivn
kvfdfrpgilikqlnlkspifkktssgghfgrseeeflwekpiilq

    Sequence, based on observed residues (ATOM records): (download) 
    >6c07C (C:)
eqflfssesvcsghpdklcdqisdaildacleqdpesfvacetctktgfimvfgeittka
nvnyervvretvkeigydseekgldyktmdviikleqqnvedigagdqgmmfgyatnetk
elmplthvlatsitreldyirvkgvssrvgwlrpdgkaqvtveynckhgvlipkrihtil
vsvqhdenieneeirefvlenvikkvcpsdlmdketrilinpsgrftiggpaadagltgr
kiivdtyggwgahgggafsgkdatkvdrsgaymarlvaksivfsglcsrclvqvsygigi
arplslyintfgtakdgyndaklleivnkvfdfrpgilikqlnlkspifkktssgghfgr
seeeflwekpiilq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6c07D (D:)
mdssrfsgnkstytdlqttseqflfssesvcsghpdklcdqisdaildacleqdpesfva
cetctktgfimvfgeittkanvnyervvretvkeigydseekgldyktmdviikleqqsn
qiagcvhvdknvedigagdqgmmfgyatnetkelmplthvlatsitreldyirvkgvssr
vgwlrpdgkaqvtveynckhgvlipkrihtilvsvqhdenieneeirefvlenvikkvcp
sdlmdketrilinpsgrftiggpaadagltgrkiivdtyggwgahgggafsgkdatkvdr
sgaymarlvaksivfsglcsrclvqvsygigiarplslyintfgtakdgyndaklleivn
kvfdfrpgilikqlnlkspifkktssgghfgrseeeflwekpiilq

    Sequence, based on observed residues (ATOM records): (download) 
    >6c07D (D:)
flfssesvcsghpdklcdqisdaildacleqdpesfvacetctktgfimvfgeittkanv
nyervvretvkeigydseekgldyktmdviikleqdigagdqgmmfgyatnetkelmplt
hvlatsitreldyirvkgvssrvgwlrpdgkaqvtveynckhgvlipkrihtilvsvqhd
enieneeirefvlenvikkvcpsdlmdketrilinpsgrftiggpaadagltgrkiivdt
yggwgahgggafsgkdatkvdrsgaymarlvaksivfsglcsrclvqvsygigiarplsl
yintfgtakdgyndaklleivnkvfdfrpgilikqlnlkspifkktssgghfgrseeefl
wekpiilq