PDB entry 5xrq

View 5xrq on RCSB PDB site
Description: Crystal structure of human monoclonal antibody H3v-47
Class: immune system
Keywords: antibody, Fab, heavy chain, light chain, IMMUNE SYSTEM
Deposited on 2017-06-09, released 2018-07-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab H3v-47 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Gene: DKFZp686P15220
    Database cross-references and differences (RAF-indexed):
    • PDB 5XRQ (Start-121)
    • Uniprot Q6N089 (122-End)
    Domains in SCOPe 2.08: d5xrqa_
  • Chain 'B':
    Compound: Fab H3v-47 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5XRQ (0-104)
    • Uniprot Q8TCD0 (105-End)
    Domains in SCOPe 2.08: d5xrqb1, d5xrqb2
  • Chain 'H':
    Compound: Fab H3v-47 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Gene: DKFZp686P15220
    Database cross-references and differences (RAF-indexed):
    • PDB 5XRQ (0-121)
    • Uniprot Q6N089 (122-End)
    Domains in SCOPe 2.08: d5xrqh_
  • Chain 'L':
    Compound: Fab H3v-47 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5XRQ (0-104)
    • Uniprot Q8TCD0 (105-End)
    Domains in SCOPe 2.08: d5xrql1, d5xrql2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xrqA (A:)
qvqlvqsgaevkkpgssvrvsckasgdtfssysitwvrqapghglqwmggifpifgstny
aqkfddrltittddssrtvymeltslrledtavyycargaskvepaapaysdafdmwgqg
tlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtf
pavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5xrqA (A:)
vqlvqsgaevkkpgssvrvsckasgdtfssysitwvrqapghglqwmggifpifgstnya
qkfddrltittddssrtvymeltslrledtavyycargaskvepaapaysdafdmwgqgt
lvtvssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkrve

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5xrqB (B:)
divmtqspgtlslspgeratlscrtsqgvsssylawyqqkpgqaprllisgsssratgip
drfsgsgsgrdftltisrlepedsavyycqqyatsptfgqgtrveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5xrqB (B:)
divmtqspgtlslspgeratlscrtsqgvsssylawyqqkpgqaprllisgsssratgip
drfsgsgsgrdftltisrlepedsavyycqqyatsptfgqgtrveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrg

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5xrqH (H:)
qvqlvqsgaevkkpgssvrvsckasgdtfssysitwvrqapghglqwmggifpifgstny
aqkfddrltittddssrtvymeltslrledtavyycargaskvepaapaysdafdmwgqg
tlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtf
pavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5xrqH (H:)
qvqlvqsgaevkkpgssvrvsckasgdtfssysitwvrqapghglqwmggifpifgstny
aqkfddrltittddssrtvymeltslrledtavyycargaskvepaapaysdafdmwgqg
tlvtvssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrve

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >5xrqL (L:)
divmtqspgtlslspgeratlscrtsqgvsssylawyqqkpgqaprllisgsssratgip
drfsgsgsgrdftltisrlepedsavyycqqyatsptfgqgtrveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5xrqL (L:)
divmtqspgtlslspgeratlscrtsqgvsssylawyqqkpgqaprllisgsssratgip
drfsgsgsgrdftltisrlepedsavyycqqyatsptfgqgtrveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge