PDB entry 5vsv

View 5vsv on RCSB PDB site
Description: Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: TIM barrel, IMPDH, CSGID, Structural Genomics, Center for Structural Genomics of Infectious Diseases, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex
Deposited on 2017-05-12, released 2017-05-24
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-05-24, with a file datestamp of 2017-05-19.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens [TaxId:1502]
    Gene: guaB_2, guaB, ERS852446_02285, JFP838_13815
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5vsva_
  • Chain 'B':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens [TaxId:1502]
    Gene: guaB_2, guaB, ERS852446_02285, JFP838_13815
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5vsvb_
  • Chain 'C':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens [TaxId:1502]
    Gene: guaB_2, guaB, ERS852446_02285, JFP838_13815
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5vsvc_
  • Chain 'D':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens [TaxId:1502]
    Gene: guaB_2, guaB, ERS852446_02285, JFP838_13815
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5vsvd_
  • Heterogens: IMP, 8KY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5vsvA (A:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >5vsvA (A:)
arilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiam
areggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivl
dtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsictt
rivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagc
eeapgaieiyqgrsykvyrgmgslgamakfvpegvegriaykghladtiyqliggiksgm
gylgaptlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5vsvB (B:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >5vsvB (B:)
ilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiamar
eggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivldt
ahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttri
vagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagcee
apgaieiyqgrsykvyrgmgslgamakfvpegvegriaykghladtiyqliggiksgmgy
lgaptlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5vsvC (C:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >5vsvC (C:)
rilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiama
reggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivld
tahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttr
ivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagce
eapgaieiyqgrsykvyrgmgslgamakkfvpegvegriaykghladtiyqliggiksgm
gylgaptlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5vsvD (D:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >5vsvD (D:)
lktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiamare
ggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivldta
hghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttriv
agvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagceea
pgaieiyqgrsykvyrgmgslgamakkfvpegvegriaykghladtiyqliggiksgmgy
lgaptlenlyenanfvvqtsagfreshphdinitkeapnys