PDB entry 5vfd

View 5vfd on RCSB PDB site
Description: Diazabicyclooctenone ETX2514 bound to Class D beta lactamase OXA-24 from A. baumannii
Class: hydrolase/hydrolase inhibitor
Keywords: ETX2514, beta-lactamase, PBP Gram negative, Astrazeneca, Entasis, A. baumannii, covalent inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2017-04-07, released 2017-06-07
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-06-07, with a file datestamp of 2017-06-02.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: blaOXA-33, bla-OXA-40, blaOXA-24, blaOXA-40, oxa-24, oxa40, A8G88_08245
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5vfda_
  • Heterogens: SO4, 9CP, 9CM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5vfdA (A:)
hissqqhekaiksyfdeaqtqgviiikegknlstygnalarankeyvpastfkmlnalig
lenhkattneifkwdgkkrtypmwekdmtlgeamalsavpvyqelarrtglelmqkevkr
vnfgntnigtqvdnfwlvgplkitpvqevnfaddlahnrlpfkletqeevkkmllikevn
gskiyaksgwgmgvtpqvgwltgwveqangkkipfslnlemkegmsgsirneitykslen
lgii