PDB entry 5v4y

View 5v4y on RCSB PDB site
Description: X-ray crystal structure of wild type HIV-1 protease in complex with GRL-09510
Class: hydrolase/hydrolase inhibitor
Keywords: GRL-09510, HIV-1 PROTEASE, PROTEASE-INHIBITOR, Pyran, Furan, NONPEPTIDIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, CROWN-THF
Deposited on 2017-03-11, released 2017-09-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-09-13, with a file datestamp of 2017-09-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72874 (0-98)
      • engineered mutation (66)
      • engineered mutation (94)
    Domains in SCOPe 2.06: d5v4ya_
  • Heterogens: 8FM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5v4yA (A:)
    pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieiaghkaigtvlvgptpvniigrnlltqigatlnf