PDB entry 5tr2

View 5tr2 on RCSB PDB site
Description: Crystal structure of the D263G missense variant of human PGM1
Class: isomerase
Keywords: isomerase, phosphohexomutase, enzyme
Deposited on 2016-10-25, released 2017-02-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoglucomutase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PGM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36871 (23-584)
      • expression tag (22)
      • conflict (285)
    Domains in SCOPe 2.07: d5tr2a1, d5tr2a2, d5tr2a3, d5tr2a4, d5tr2a5
  • Chain 'B':
    Compound: Phosphoglucomutase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PGM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36871 (Start-584)
      • conflict (285)
    Domains in SCOPe 2.07: d5tr2b1, d5tr2b2, d5tr2b3, d5tr2b4
  • Heterogens: SO4, CA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5tr2A (A:)
mhhhhhhssgvdlgtenlyfqsnmvkivtvktqayqdqkpgtsglrkrvkvfqssanyae
nfiqsiistvepaqrqeatlvvggdgrfymkeaiqliariaaangigrlvigqngilstp
avsciirkikaiggiiltashnpggpngdfgikfnisnggpapeaitdkifqisktieey
avcpdlkvdlgvlgkqqfdlenkfkpftveivdsveayatmlrsifdfsalkellsgpnr
lkiridamhgvvgpyvkkilceelgapansavncvpledfgghhpgpnltyaadlvetmk
sgehdfgaafdgdgdrnmilgkhgffvnpsdsvaviaanifsipyfqqtgvrgfarsmpt
sgaldrvasatkialyetptgwkffgnlmdasklslcgeesfgtgsdhirekdglwavla
wlsilatrkqsvedilkdhwqkygrnfftrydyeeveaegankmmkdlealmfdrsfvgk
qfsandkvytvekadnfeysdpvdgsisrnqglrliftdgsrivfrlsgtgsagatirly
idsyekdvakinqdpqvmlaplisialkvsqlqertgrtaptvit

    Sequence, based on observed residues (ATOM records): (download) 
    >5tr2A (A:)
nmvkivtvktqayqdqkpgtsglrkrvkvfqssanyaenfiqsiistvepaqrqeatlvv
ggdgrfymkeaiqliariaaangigrlvigqngilstpavsciirkikaiggiiltashn
pggpngdfgikfnisnggpapeaitdkifqisktieeyavcpdlkvdlgvlgkqqfdlen
kfkpftveivdsveayatmlrsifdfsalkellsgpnrlkiridamhgvvgpyvkkilce
elgapansavncvpledfgghhpgpnltyaadlvetmksgehdfgaafdgdgdrnmilgk
hgffvnpsdsvaviaanifsipyfqqtgvrgfarsmptsgaldrvasatkialyetptgw
kffgnlmdasklslcgeesfgtgsdhirekdglwavlawlsilatrkqsvedilkdhwqk
ygrnfftrydyeeveaegankmmkdlealmfdrsfvgkqfsandkvytvekadnfeysdp
vdgsisrnqglrliftdgsrivfrlsgtagatirlyidsyekdvakinqdpqvmlaplis
ialkvsqlqertgrtaptvit

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5tr2B (B:)
mhhhhhhssgvdlgtenlyfqsnmvkivtvktqayqdqkpgtsglrkrvkvfqssanyae
nfiqsiistvepaqrqeatlvvggdgrfymkeaiqliariaaangigrlvigqngilstp
avsciirkikaiggiiltashnpggpngdfgikfnisnggpapeaitdkifqisktieey
avcpdlkvdlgvlgkqqfdlenkfkpftveivdsveayatmlrsifdfsalkellsgpnr
lkiridamhgvvgpyvkkilceelgapansavncvpledfgghhpgpnltyaadlvetmk
sgehdfgaafdgdgdrnmilgkhgffvnpsdsvaviaanifsipyfqqtgvrgfarsmpt
sgaldrvasatkialyetptgwkffgnlmdasklslcgeesfgtgsdhirekdglwavla
wlsilatrkqsvedilkdhwqkygrnfftrydyeeveaegankmmkdlealmfdrsfvgk
qfsandkvytvekadnfeysdpvdgsisrnqglrliftdgsrivfrlsgtgsagatirly
idsyekdvakinqdpqvmlaplisialkvsqlqertgrtaptvit

    Sequence, based on observed residues (ATOM records): (download) 
    >5tr2B (B:)
vkivtvktqayqdqkpgtsglrkrvkvfqssanyaenfiqsiistvepaqrqeatlvvgg
dgrfymkeaiqliariaaangigrlvigqngilstpavsciirkikaiggiiltashnpg
gpngdfgikfnisnggpapeaitdkifqisktieeyavcpdlkvdlgvlgkqqfdlenkf
kpftveivdsveayatmlrsifdfsalkellsrlkiridamhgvvgpyvkkilceelgap
ansavncvpledfgghhpgpnyaadlvetmksgehdfgaafdgdgdrnmilgkhgffvnp
sdsvaviaanifsipyfqqtgvrgfarsmptsgaldrvasatkialyetptgwkffgnlm
dasklslcgeesfgtgsdhirekdglwavlawlsilatrkqsvedilkdhwqkygrnfft
rydyeeveaegankmmkdlealmfdrsfvgkqfsandkvytvekadnfeysdpvdgsisr
nqglrliftdgsrivfrlsagatirlyidsyekdvakinqdpqvmlaplisialkvsqlq
ertgrtaptvit