PDB entry 5lzi

View 5lzi on RCSB PDB site
Description: Porcine heat-labile enterotoxin R13H in complex with inhibitor MM146
Class: toxin
Keywords: heat-labile enterotoxin, inhibitor, cholera, toxin
Deposited on 2016-09-29, released 2017-05-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-06-07, with a file datestamp of 2017-06-02.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: heat-labile enterotoxin b chain
    Species: Escherichia coli [TaxId:562]
    Gene: eltB, ltpB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32890 (0-102)
      • engineered mutation (12)
    Domains in SCOPe 2.08: d5lzia_
  • Chain 'B':
    Compound: heat-labile enterotoxin b chain
    Species: Escherichia coli [TaxId:562]
    Gene: eltB, ltpB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32890 (0-102)
      • engineered mutation (12)
    Domains in SCOPe 2.08: d5lzib_
  • Chain 'C':
    Compound: heat-labile enterotoxin b chain
    Species: Escherichia coli [TaxId:562]
    Gene: eltB, ltpB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32890 (0-102)
      • engineered mutation (12)
    Domains in SCOPe 2.08: d5lzic_
  • Chain 'D':
    Compound: heat-labile enterotoxin b chain
    Species: Escherichia coli [TaxId:562]
    Gene: eltB, ltpB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32890 (0-102)
      • engineered mutation (12)
    Domains in SCOPe 2.08: d5lzid_
  • Chain 'E':
    Compound: heat-labile enterotoxin b chain
    Species: Escherichia coli [TaxId:562]
    Gene: eltB, ltpB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32890 (0-102)
      • engineered mutation (12)
    Domains in SCOPe 2.08: d5lzie_
  • Heterogens: GOL, 7BQ, PEG, 7DB, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5lziA (A:)
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  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5lziB (B:)
apqtitelcseyhntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5lziC (C:)
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qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5lziD (D:)
apqtitelcseyhntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5lziE (E:)
apqtitelcseyhntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn