SCOPe 2.06: Structural Classification of Proteins

PDB entry 5lxb

View 5lxb on RCSB PDB site
Description: Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with palonosetron
Class: acetylcholine binding protein
Keywords: Cys-loop receptor, 5-HT3 receptor, acetylcholine binding protein
Deposited on 2016-09-20, released 2016-10-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-10-12, with a file datestamp of 2016-10-07.
Experiment type: XRAY
Resolution: 2.34 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxba_
Chain 'B':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbb_
Chain 'C':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbc_
Chain 'D':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbd_
Chain 'E':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbe_
Chain 'F':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbf_
Chain 'G':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbg_
Chain 'H':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbh_
Chain 'I':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbi_
Chain 'J':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8
  - conflict (59)
  - conflict (71)
  - conflict (73)
  - conflict (154)
Domains in SCOPe 2.06: d5lxbj_
Heterogens: NAG, 7A9, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>5lxbA (A:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvywerqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfdhhhh
hh