PDB entry 5lsp

View 5lsp on RCSB PDB site
Description: 107_A07 Fab in complex with fragment of the Met receptor
Class: transferase
Keywords: Fab, beta propeller, Ig-like domain, cell signalling, Met receptor, antibody binding, transferase
Deposited on 2016-09-05, released 2017-09-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: 107_A07 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5LSP (0-End)
    Domains in SCOPe 2.08: d5lsph_
  • Chain 'L':
    Compound: 107_A07 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5LSP
    Domains in SCOPe 2.08: d5lspl1, d5lspl2
  • Chain 'P':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: 107_A07 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5LSP (0-End)
    Domains in SCOPe 2.08: d5lsps_
  • Chain 'T':
    Compound: 107_A07 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5LSP
    Domains in SCOPe 2.08: d5lspt1, d5lspt2
  • Chain 'X':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08581 (3-End)
      • expression tag (1-2)
  • Chain 'Y':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08581 (3-End)
      • expression tag (1-2)
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5lspH (H:)
qmqlvqsgaevkkpgapvkvsckvsgytftdyymhwvqqapgkglewmglvdpedgetiy
aekfqgrvtitadtstdtaymelsslrsedtavyycatdattpywgmmwwgqgtlvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >5lspH (H:)
qmqlvqsgaevkkpgapvkvsckvsgytftdyymhwvqqapgkglewmglvdpedgetiy
aekfqgrvtitadtstdtaymelsslrsedtavyycatdattpywgmmwwgqgtlvtvss
astkgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysl
ssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >5lspL (L:)
asdiqmiqspsslsasvgdrvtitcqasqdisnylnwyqqkpgrapkvliydasnletgv
psrfsgsgsgteftltisnlrpddfatyycqqgdsfpltfgggtkveikraaaapsvfif
ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
ltlskadyekhklyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5lspL (L:)
diqmiqspsslsasvgdrvtitcqasqdisnylnwyqqkpgrapkvliydasnletgvps
rfsgsgsgteftltisnlrpddfatyycqqgdsfpltfgggtkveikraaaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhklyacevthqglsspvtksfnrg

  • Chain 'P':
    No sequence available.

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >5lspS (S:)
qmqlvqsgaevkkpgapvkvsckvsgytftdyymhwvqqapgkglewmglvdpedgetiy
aekfqgrvtitadtstdtaymelsslrsedtavyycatdattpywgmmwwgqgtlvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >5lspS (S:)
qmqlvqsgaevkkpgapvkvsckvsgytftdyymhwvqqapgkglewmglvdpedgetiy
aekfqgrvtitadtstdtaymelsslrsedtavyycatdattpywgmmwwgqgtlvtvss
astkgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysl
ssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >5lspT (T:)
asdiqmiqspsslsasvgdrvtitcqasqdisnylnwyqqkpgrapkvliydasnletgv
psrfsgsgsgteftltisnlrpddfatyycqqgdsfpltfgggtkveikraaaapsvfif
ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
ltlskadyekhklyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5lspT (T:)
diqmiqspsslsasvgdrvtitcqasqdisnylnwyqqkpgrapkvliydasnletgvps
rfsgsgsgteftltisnlrpddfatyycqqgdsfpltfgggtkveikraaaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhklyacevthqglsspvtksfnrg

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.