PDB entry 5l2f

View 5l2f on RCSB PDB site
Description: High Resolution Structure of Acinetobacter baumannii beta-lactamase OXA-51 I129L/K83D bound to doripenem
Class: hydrolase/antibiotic
Keywords: hydrolase, antibiotic, beta-lactamase, hydrolase-antibiotic complex
Deposited on 2016-08-01, released 2016-09-28
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-09-28, with a file datestamp of 2016-09-23.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: oxa-51, blaOXA-51, AQ480_08190
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5QT35 (Start-249)
      • engineered mutation (58)
      • engineered mutation (104)
    Domains in SCOPe 2.06: d5l2fa_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: oxa-51, blaOXA-51, AQ480_08190
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5QT35 (Start-249)
      • engineered mutation (58)
      • engineered mutation (104)
    Domains in SCOPe 2.06: d5l2fb_
  • Chain 'C':
    Compound: Beta-lactamase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: oxa-51, blaOXA-51, AQ480_08190
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5QT35 (Start-249)
      • engineered mutation (58)
      • engineered mutation (104)
    Domains in SCOPe 2.06: d5l2fc_
  • Chain 'D':
    Compound: Beta-lactamase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: oxa-51, blaOXA-51, AQ480_08190
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5QT35 (Start-249)
      • engineered mutation (58)
      • engineered mutation (104)
    Domains in SCOPe 2.06: d5l2fd_
  • Heterogens: 4J6, ACT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5l2fA (A:)
mnpnhsasksdekaekiknlfnevhttgvlviqqgqtqqsygndlarasteyvpastfdm
lnaliglehhkatttevfkwdgqkrlfpewekdmtlgdamkasalpvyqdlarriglelm
skevkrvgygnadigtqvdnfwlvgplkitpqqeaqfayklanktlpfspkvqdevqsml
fieekngnkiyaksgwgwdvdpqvgwltgwvvqpqgnivafslnlemkkgipssvrkeit
yksleqlgil

    Sequence, based on observed residues (ATOM records): (download) 
    >5l2fA (A:)
ekaekiknlfnevhttgvlviqqgqtqqsygndlarasteyvpastfdmlnaliglehhk
atttevfkwdgqkrlfpewekdmtlgdamkasalpvyqdlarriglelmskevkrvgygn
adigtqvdnfwlvgplkitpqqeaqfayklanktlpfspkvqdevqsmlfieekngnkiy
aksgwgwdvdpqvgwltgwvvqpqgnivafslnlemkkgipssvrkeityksleqlgil

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5l2fB (B:)
mnpnhsasksdekaekiknlfnevhttgvlviqqgqtqqsygndlarasteyvpastfdm
lnaliglehhkatttevfkwdgqkrlfpewekdmtlgdamkasalpvyqdlarriglelm
skevkrvgygnadigtqvdnfwlvgplkitpqqeaqfayklanktlpfspkvqdevqsml
fieekngnkiyaksgwgwdvdpqvgwltgwvvqpqgnivafslnlemkkgipssvrkeit
yksleqlgil

    Sequence, based on observed residues (ATOM records): (download) 
    >5l2fB (B:)
dekaekiknlfnevhttgvlviqqgqtqqsygndlarasteyvpastfdmlnaliglehh
katttevfkwdgqkrlfpewekdmtlgdamkasalpvyqdlarriglelmskevkrvgyg
nadigtqvdnfwlvgplkitpqqeaqfayklanktlpfspkvqdevqsmlfieekngnki
yaksgwgwdvdpqvgwltgwvvqpqgnivafslnlemkkgipssvrkeityksleqlgil

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5l2fC (C:)
mnpnhsasksdekaekiknlfnevhttgvlviqqgqtqqsygndlarasteyvpastfdm
lnaliglehhkatttevfkwdgqkrlfpewekdmtlgdamkasalpvyqdlarriglelm
skevkrvgygnadigtqvdnfwlvgplkitpqqeaqfayklanktlpfspkvqdevqsml
fieekngnkiyaksgwgwdvdpqvgwltgwvvqpqgnivafslnlemkkgipssvrkeit
yksleqlgil

    Sequence, based on observed residues (ATOM records): (download) 
    >5l2fC (C:)
dekaekiknlfnevhttgvlviqqgqtqqsygndlarasteyvpastfdmlnaliglehh
katttevfkwdgqkrlfpewekdmtlgdamkasalpvyqdlarriglelmskevkrvgyg
nadigtqvdnfwlvgplkitpqqeaqfayklanktlpfspkvqdevqsmlfieekngnki
yaksgwgwdvdpqvgwltgwvvqpqgnivafslnlemkkgipssvrkeityksleqlgil

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5l2fD (D:)
mnpnhsasksdekaekiknlfnevhttgvlviqqgqtqqsygndlarasteyvpastfdm
lnaliglehhkatttevfkwdgqkrlfpewekdmtlgdamkasalpvyqdlarriglelm
skevkrvgygnadigtqvdnfwlvgplkitpqqeaqfayklanktlpfspkvqdevqsml
fieekngnkiyaksgwgwdvdpqvgwltgwvvqpqgnivafslnlemkkgipssvrkeit
yksleqlgil

    Sequence, based on observed residues (ATOM records): (download) 
    >5l2fD (D:)
ekaekiknlfnevhttgvlviqqgqtqqsygndlarasteyvpastfdmlnaliglehhk
atttevfkwdgqkrlfpewekdmtlgdamkasalpvyqdlarriglelmskevkrvgygn
adigtqvdnfwlvgplkitpqqeaqfayklanktlpfspkvqdevqsmlfieekngnkiy
aksgwgwdvdpqvgwltgwvvqpqgnivafslnlemkkgipssvrkeityksleqlgil